Format

Send to

Choose Destination
J Physiol. 1999 May 1;516 ( Pt 3):631-8.

Molecular insights into the physiology of the 'thin film' of airway surface liquid.

Author information

1
Cystic Fibrosis/Pulmonary Research and Treatment Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7248, USA. rboucher@med.unc.edu

Abstract

The epithelia that line the airways of the lung exhibit two general functions: (1) airway epithelia in all regions 'defend' the lung against infectious and noxious agents; and (2) airway epithelia in the proximal regions replenish water lost from airway surfaces, i.e. the 'insensible water loss', consequent to conditioning inspired air. How airway epithelia perform both functions, and co-ordinate them in health and disease, is the subject of this review.

PMID:
10200413
PMCID:
PMC2269304
DOI:
10.1111/j.1469-7793.1999.0631u.x
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Wiley Icon for PubMed Central
Loading ...
Support Center