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Infect Dis Clin North Am. 1999 Mar;13(1):61-81, vi.

Herpesvirus vaccines. Development, controversies, and applications.

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1
Food and Drug Administration, Center for Biologics Evaluation and Research, Office of Vaccines Research and Review, Bethesda, Maryland, USA.

Abstract

Herpesviruses present difficult challenges in vaccine development because of their ability to evade immune clearance. Data and recommendations regarding the live-attenuated varicella vaccine are discussed. Approaches to developing vaccines to prevent herpes simplex virus (HSV), cytomegalovirus (CMV), and Epstein-Barr virus (EBV)-associated illnesses also are considered.

PMID:
10198792
[Indexed for MEDLINE]
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