Send to

Choose Destination
Int J Obes Relat Metab Disord. 1999 Mar;23(3):287-92.

Diet induced thermogenesis measured over 24h in a respiration chamber: effect of diet composition.

Author information

Department of Human Biology, Maastricht University, The Netherlands.



To study the effect of diet composition on diet-induced thermogenesis (DIT) over 24h in a respiration chamber.


Eight healthy female volunteers (age 27 +/- 3 y; body mass index, BMI 23 +/- 3 kg/m2). DIETS: A high protein and carbohydrate (HP/C) (60:10:30; percentage energy (E%)carbohydrate, fat and protein, respectively) and high fat (HF) (30:60:10 respectively) diet, both isoenergetic, isovolumetric, composed of normal food items and matched for organoleptic properties (taste, smell, appearance).


Subjects spent two 36h periods each in a respiration chamber consuming both test diets in random order. Components of 24h energy expenditure (24h EE): sleeping metabolic rate, DIT and activity induced energy expenditure were measured.


DIT was higher in all subjects while on the HP/C diet (1295 kJ/d vs 931 kJ/d; 14.6% vs 10.5% of energy intake; P < 0.02). There was no significant difference in other components or total 24h EE, although there was a trend towards higher EE on the HP/C diet.


A high protein and carbohydrate diet induces a greater thermic response in healthy individuals when compared to a high fat diet.

[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center