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Biosci Biotechnol Biochem. 1999 Feb;63(2):430-2.

Methylation of tea catechins by rat liver homogenates.

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1
Food Research Institute, Mitsui Norin Co. Ltd., Shizuoka, Japan.

Abstract

Methylation of (-)-epigallocatechin (EGC), (-)-epicatechin gallate (ECg), and (-)-epigallocatechin gallate (EGCg) was carried out with a rat liver homogenate and S-adenosyl-L-methionine. A structural analysis of the reaction products by MS and NMR showed that 4'-O-methyl EGC, 4"-O-methyl ECg, and 4"-O-methyl EGCg had been formed from EGC, ECg, and EGCg, respectively. These results suggest that methylation may be one of the metabolic pathways to the catechins.

PMID:
10192923
DOI:
10.1271/bbb.63.430
[Indexed for MEDLINE]
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