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Arch Int Pharmacodyn Ther. 1976 Dec;224(2):291-8.

Anti-ulcer activity of colloidal bismuth subcitrate in Shay-rats.

Abstract

The anti-ulcer action of colloidal bismuth subcitrate (CBS) was tested in rats with a ligated pylorus (the Shay preparation). The liquid form used in the clinic displayed a dose-related inhibition of gastric ulceration. the recently developed solid form appeared to be just as effective. On the other hand, non-processed, non-colloidal bismuth salts and the CBS vehicle blank were completely inactive. The anti-ulcer activity of CBS was found to be unrelated to its buffering capacity.

PMID:
1015926
[Indexed for MEDLINE]

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