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Science. 1999 Apr 2;284(5411):151-3.

ROUGH SHEATH2: a Myb protein that represses knox homeobox genes in maize lateral organ primordia.

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1
Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511, USA.

Abstract

The regulation of members of the knotted1-like homeobox (knox) gene family is required for the normal initiation and development of lateral organs. The maize rough sheath2 (rs2) gene, which encodes a Myb-domain protein, is expressed in lateral organ primordia and their initials. Mutations in the rs2 gene permit ectopic expression of knox genes in leaf and floral primordia, causing a variety of developmental defects. Ectopic KNOX protein accumulation in rs2 mutants occurs in a subset of the normal rs2-expressing cells. This variegated accumulation of KNOX proteins in rs2 mutants suggests that rs2 represses knox expression through epigenetic means.

PMID:
10102816
[Indexed for MEDLINE]
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