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J Bacteriol. 1999 Apr;181(7):2252-6.

Oxygen depletion-induced dormancy in Mycobacterium bovis BCG.

Author information

1
Institute of Molecular and Cell Biology, Singapore 117609, Republic of Singapore.

Abstract

Gradual depletion of oxygen causes the shift-down of aerobic growing Mycobacterium bovis BCG to an anaerobic synchronized state of nonreplicating persistence. The persistent culture shows induction of glycine dehydrogenase and alpha-crystallin-like protein and is sensitive to metronidazole.

PMID:
10094705
PMCID:
PMC93640
[Indexed for MEDLINE]
Free PMC Article

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