Format

Send to

Choose Destination
J Virol Methods. 1999 Feb;77(2):207-15.

Susceptibility of human and non-human cell lines to HCV infection as determined by the centrifugation-facilitated method.

Author information

1
Department of Biomedicine and Retrovirus Center, Università di Pisa, Italy.

Abstract

The centrifugation-facilitated inoculation method was used to test 51 human and non-human cell lines for ability to support HCV replication. As determined by nested RT-PCR, one fifth of the cell lines tested were virus positive 15 days post inoculation suggesting that the centrifugation-facilitated inoculation is an efficient method for cell infection with HCV. However, virus production by infected cultures remained of low grade, thus showing that the unknown factors which limit HCV replication in vitro are not overcome by the procedure.

PMID:
10092144
DOI:
10.1016/s0166-0934(98)00155-4
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center