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Am J Med. 1999 Jan 25;106(1A):43S-45S.

Progress report: the Arizona phase III study of the effect of wheat bran fiber on recurrence of adenomatous colon polyps.

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Department of Medicine, University of Arizona Health Sciences Center, and the VA Medical Center, Tucson 85724-5028, USA.


A double-blind, placebo-controlled Phase III cancer prevention trial in subjects with previous resection of adenomatous colon polyps is nearing completion. The study's primary objective is to evaluate the effects of daily dietary supplementation with large (13.5 g/day) versus small (2.0 g/day) doses of wheat bran fiber for 3 years. A summary of the study design and a progress report are presented.

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