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Genet Anal. 1999 Feb;14(5-6):181-6.

Enzymatic methods for mutation scanning.

Author information

1
DNA Laboratory, St. James's University Hospital, Leeds, UK. gtaylor@hgmp.mrc.ac.uk

Abstract

Enzymatic methods for mutation scanning still lack the sensitivity and specificity of the chemical cleavage of mismatch method. However developments in our understanding of the mismatch recognition process should lead to improvements. Several promising candidates exist with potential for more specific and sensitive mutation detection.

PMID:
10084112
DOI:
10.1016/s1050-3862(98)00029-1
[Indexed for MEDLINE]

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