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Curr Biol. 1999 Mar 11;9(5):R160-3.

Actin polymerization: Where the WASP stings.

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1
Departments of Cell and Developmental Biology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6018, USA.

Abstract

How do extracellular signals induce actin polymerization, as required for many cellular responses? Key signal transducers, such as the small GTPases Cdc42 and Rac, have now been shown to link via proteins of the WASP family to the Arp2/3 complex, which nucleates actin polymerization.

PMID:
10074445
[Indexed for MEDLINE]
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