[Basophil activation test using flow cytometry in Hymenoptera venom allergy]

Allerg Immunol (Paris). 1999 Jan;31(1):11-4.
[Article in French]

Abstract

The basophil activation test (TAB) clearly shows evidence to Hymenoptera venoms. Comparison of the TAB value with the clinical history allows fixation of a threshold that will anticipate the type of clinical reaction by the TAB value. For the technique of TAB 3 dilutions are used. The basophil activation values produce a threshold for each dilution. For the first dilution the threshold is 50% activation: below this threshold, 70% of patients would have a local or systemic reaction and above this threshold, 70% of patients would have a systemic allergic reaction.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Allergens / adverse effects*
  • Allergens / pharmacology
  • Anaphylaxis / etiology
  • Anaphylaxis / immunology
  • Basophil Degranulation Test*
  • Basophils / drug effects
  • Bee Venoms / adverse effects*
  • Bee Venoms / pharmacology
  • Child
  • Evaluation Studies as Topic
  • Female
  • Flow Cytometry*
  • Humans
  • Hypersensitivity, Immediate / classification
  • Hypersensitivity, Immediate / etiology*
  • Hypersensitivity, Immediate / immunology
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Risk
  • Wasp Venoms / adverse effects*
  • Wasp Venoms / pharmacology

Substances

  • Allergens
  • Bee Venoms
  • Wasp Venoms