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Br J Neurosurg. 1998 Aug;12(4):313-7.

The neuronal cytoskeleton in acute brain injury.

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  • 1Department of Neurosurgery, Institute of Neurological Sciences, Glasgow, UK.


The microtubules, neurofilaments and microfilaments of the neuronal cytoskeleton are essential for the normal functioning of the neurone. Recent studies have shown that disruption of the cytoskeleton may represent a final pathway in many types of neuronal cell injury with both the somato-dendritic and axonal cytoskeleton being affected. This review discusses the current evidence on the role of the neuronal cytoskeleton in the pathogenesis of traumatic brain damage.

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