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Curr Opin Microbiol. 1998 Dec;1(6):687-92.

Dimorphism and virulence in Candida albicans.

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Department of Microbiology, Institute of Cancer Research, Columbia University, 701 West 168th Street, New York, NY 10032, USA.


Two regulatory pathways govern filamentation in the pathogenic fungus Candida albicans. Recent virulence studies of filamentation regulatory mutants argue that both yeast and filamentous forms have roles in infection. Filamentation control pathways seem closely related in C. albicans and in Saccharomyces cerevisiae, thus permitting speculation about C. albicans filamentation genes not yet discovered.

[Indexed for MEDLINE]

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