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Curr Opin Microbiol. 1998 Apr;1(2):197-203.

Protein chaperones and the heat shock response in Saccharomyces cerevisiae.

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Department of Biological Chemistry, University of Michigan Medical School, 1301 Catherine Road, Ann Arbor, MI 48109-0606, USA.


Recent studies have shed new light on the complexities of the heat shock response in yeast. Multiple pathways for transcriptional induction of both classic and novel heat shock proteins are emerging together with a more detailed understanding of the interactions between protein chaperones and their physiological targets. New roles for heat shock proteins in defense and recovery from the impacts of thermal stress on critical cellular processes have expanded our understanding of these elaborate and ubiquitous proteins.

[Indexed for MEDLINE]

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