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Curr Opin Microbiol. 1998 Feb;1(1):82-7.

The diverse habitats of obligate intracellular parasites.

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Host-Parasite Interactions Section, Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, National Institute for Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA.


Bacterial obligate intracellular parasites have evolved diverse mechanisms for evasion of host cellular defenses. These mechanisms involve adaptations for survival in distinct intracellular compartments. Intracellular niches inhabited by obligate intracellular parasites include the cytoplasm, arrested early endosomes, lysosomes, and vesicles that do not fuse with the endosomal compartment but intersect with an exocytic pathway.

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