Abstract
Naturally occurring substances which can prevent and treat diabetic complications were sought by examining ethanol extracts prepared from Korean forest plants for their inhibitory effects on rat lens aldose reductase activity in vitro. Among the plants examined, Acer ginnala, Illicium religiosum and Cornus macrophylla exerted the most strong inhibitory activity on aldose reductase.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aldehyde Reductase / antagonists & inhibitors*
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Animals
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Diabetes Mellitus / drug therapy
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Drug Evaluation, Preclinical
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Enzyme Inhibitors / isolation & purification
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Enzyme Inhibitors / pharmacology*
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Humans
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In Vitro Techniques
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Korea
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Lens, Crystalline / enzymology*
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Magnoliopsida
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Male
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Plant Extracts / isolation & purification
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Plant Extracts / pharmacology*
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Plants, Medicinal
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Rats
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Rats, Sprague-Dawley
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Trees
Substances
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Enzyme Inhibitors
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Plant Extracts
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Aldehyde Reductase