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Curr Opin Microbiol. 1999 Feb;2(1):40-5.

Virulence gene regulation by peptides in staphylococci and other Gram-positive bacteria.

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Skirball Institute of Biomolecular Medicine New York University School of Medicine 540 First Ave 2nd floor New York NY 10016 USA.


In staphylococci, autoinducing peptides activate agr. a global regulator of the expression of genes encoding virulence factors and other exoproteins. During the past year, there have been major advances in the structure-function analysis of these peptides and the regulation of a virulence factor by an autoinducing peptide in pneumococci has been demonstrated.

[Indexed for MEDLINE]

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