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Curr Opin Immunol. 1999 Feb;11(1):28-33.

Lung surfactant proteins involved in innate immunity.

Author information

1
MRC Immunochemistry Unit, Department of Biochemistry, University of Oxford, UK. eggleton@bioch.ox.ac.uk.

Abstract

The two lung surfactant collectins, surfactant protein (SP)-A and SP-D, are involved in host defence against infectious and allergenic agents via enhancement of killing and clearance by macrophages and neutrophils. Recent gene-knockout, protein engineering and physiological studies have emphasised the roles that SP-A and SP-D play in acute inflammatory responses.

PMID:
10047533
DOI:
10.1016/s0952-7915(99)80006-5
[Indexed for MEDLINE]

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