Bioanalytic applications of mass spectrometry

Curr Opin Biotechnol. 1999 Feb;10(1):22-8. doi: 10.1016/s0958-1669(99)80005-6.

Abstract

Mass spectrometry has suddenly expanded out of research and assay laboratories into biology, medicine and therapeutics. Electrospray ionization and matrix-assisted laser desorption/ionization yield increased mass-range and sensitivity, leading to novel applications and sparking new analyzer designs, software, and robotics.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Carbohydrate Sequence
  • Chromatography, High Pressure Liquid
  • Glycoconjugates / chemistry*
  • Mass Spectrometry / economics
  • Mass Spectrometry / methods*
  • Mass Spectrometry / trends
  • Molecular Sequence Data
  • Oligonucleotides / chemistry*
  • Oligosaccharides / chemistry*
  • Proteins / chemistry*

Substances

  • Glycoconjugates
  • Oligonucleotides
  • Oligosaccharides
  • Proteins