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Neurosci Lett. 1999 Jan 4;259(1):65-6.

No pathogenic mutations in the persyn gene in Parkinson's disease.

Author information

1
Mayo Clinic Jacksonville, FL 32084, USA.

Abstract

The persyn (gamma-synuclein) gene is highly homologous to the alpha-synuclein gene and is highly expressed in the nervous system. It is therefore, an excellent candidate gene for Parkinson's disease. However, we have sequenced the gene in a large number of families with parkinsonism and failed to find pathogenic mutations.

PMID:
10027558
[Indexed for MEDLINE]

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