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Hum Genet. 1976 Oct 28;34(2):119-24.

Localization of factors controlling spermatogenesis in the nonfluorescent portion of the human Y chromosome long arm.


A deletion of the Y chromosome at the distal portion of band q11 was found in 6 men with normal male habitus but with azoospermia. Five of them were found during a survey of 1170 subfertile males while the sixth was karyotyped because of slight bone abnormalities. These findings, together with a review of the literature, suggest that on the distal portion of the nonfluoresecent segment of the long arm of the Y, factors are located controlling spermatogenesis.

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