G protein-activated inward rectifier potassium channel 1 isoform X1 [M - Protein

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Protein 3D Structure

Crystal structure of the S225E mutant Kir3.1 cytoplasmic pore domain

PDB: 3K6N

Source: Mus musculus

Method: X-ray Diffraction

Resolution: 2 Å

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Articles about the Kcnj3 gene

G-Protein-Gated Inwardly Rectifying Potassium (Kir3/GIRK) Channels Govern Synaptic Plasticity That Supports Hippocampal-Dependent Cognitive Functions in Male Mice. [J Neurosci. 2021]
G-Protein-Gated Inwardly Rectifying Potassium (Kir3/GIRK) Channels Govern Synaptic Plasticity That Supports Hippocampal-Dependent Cognitive Functions in Male Mice.
Djebari S, Iborra-Lázaro G, Temprano-Carazo S, Sánchez-Rodríguez I, Nava-Mesa MO, Múnera A, Gruart A, Delgado-García JM, Jiménez-Díaz L, Navarro-López JD. J Neurosci. 2021 Aug 18; 41(33):7086-7102. Epub 2021 Jul 14.
Suppression of pyramidal neuron G protein-gated inwardly rectifying K+ channel signaling impairs prelimbic cortical function and underlies stress-induced deficits in cognitive flexibility in male, but not female, mice. [Neuropsychopharmacology. 2021]
Suppression of pyramidal neuron G protein-gated inwardly rectifying K+ channel signaling impairs prelimbic cortical function and underlies stress-induced deficits in cognitive flexibility in male, but not female, mice.
Anderson EM, Loke S, Wrucke B, Engelhardt A, Demis S, O'Reilly K, Hess E, Wickman K, Hearing MC. Neuropsychopharmacology. 2021 Nov; 46(12):2158-2169. Epub 2021 Jun 23.
GIRK1-Mediated Inwardly Rectifying Potassium Current Is a Candidate Mechanism Behind Purkinje Cell Excitability, Plasticity, and Neuromodulation. [Cerebellum. 2020]
GIRK1-Mediated Inwardly Rectifying Potassium Current Is a Candidate Mechanism Behind Purkinje Cell Excitability, Plasticity, and Neuromodulation.
Lippiello P, Hoxha E, Tempia F, Miniaci MC. Cerebellum. 2020 Dec; 19(6):751-761.

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Reference sequence information

RefSeq mRNA
See reference mRNA sequence for the Kcnj3 gene (XM_030247730.2).
RefSeq protein isoforms
See 19 reference sequence protein isoforms for the Kcnj3 gene.

More about the Kcnj3 gene

Predicted to enable inward rectifier potassium channel activity. Predicted to be involved in potassium ion import across plasma membrane and...
Also Known As: GIRK-1, GIRK1, Kcnf3, K...

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G protein-activated inward rectifier potassium channel 1 isoform X1 [Mus musculus]

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