gamma-secretase subunit APH-1B isoform 2 [Homo sapiens]

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Negative evidence for a role of APH1B T27I variant in Alzheimer's disease. [Hum Mol Genet. 2020]
Negative evidence for a role of APH1B T27I variant in Alzheimer's disease.
Zhang X, Zhang C, Prokopenko D, Liang Y, Han W, Tanzi RE, Sisodia SS. Hum Mol Genet. 2020 Apr 15; 29(6):955-966.
Identification and characterization of a novel human APH-1b splice variant lacking exon 4. [Biochem Biophys Res Commun. 2005]
Identification and characterization of a novel human APH-1b splice variant lacking exon 4.
Saito S, Takahashi-Sasaki N, Araki W. Biochem Biophys Res Commun. 2005 May 20; 330(4):1068-72.
Dysregulated expression levels of APH1B in peripheral blood are associated with brain atrophy and amyloid-β deposition in Alzheimer's disease. [Alzheimers Res Ther. 2021]
Dysregulated expression levels of APH1B in peripheral blood are associated with brain atrophy and amyloid-β deposition in Alzheimer's disease.
Park YH, Pyun JM, Hodges A, Jang JW, Bice PJ, Kim S, Saykin AJ, Nho K, AddNeuroMed consortium and the Alzheimer’s Disease Neuroimaging Initiative. Alzheimers Res Ther. 2021 Nov 3; 13(1):183. Epub 2021 Nov 3.

RefSeq mRNA
See reference mRNA sequence for the APH1B gene (NM_001145646.2).
RefSeq protein isoforms
See 6 reference sequence protein isoforms for the APH1B gene.

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GlyGen glycoinformatics resource [GlyGen glycoinformatics resou...]
GlyGen glycoinformatics resource
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OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
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reagents [ExactAntigen/Labome]
reagents
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