interferon, alpha-inducible protein (clone IFI-15K) [Homo sapiens]

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Case Report: ISG15 deficiency caused by novel variants in two families and effective treatment with Janus kinase inhibition. [Front Immunol. 2023]
Case Report: ISG15 deficiency caused by novel variants in two families and effective treatment with Janus kinase inhibition.
Burleigh A, Moraitis E, Al Masroori E, Al-Abadi E, Hong Y, Omoyinmi E, Titheradge H, Stals K, Jones WD, Gait A, et al. Front Immunol. 2023; 14:1287258. Epub 2023 Dec 5.
A novel homozygous Y140X mutation of ISG15 causes diverse type I interferonopathies in sibling patients with cutaneous lesions or recurrent parenchymal pneumonia. [Clin Immunol. 2023]
A novel homozygous Y140X mutation of ISG15 causes diverse type I interferonopathies in sibling patients with cutaneous lesions or recurrent parenchymal pneumonia.
Xu Q, Li W, Zhao Q, Zhao L, Lv G, Sun G, Gao Y, Ding Y, Zhang Z, Zhou L, et al. Clin Immunol. 2023 Dec; 257:109844. Epub 2023 Nov 19.
ISG15: its roles in SARS-CoV-2 and other viral infections. [Trends Microbiol. 2023]
ISG15: its roles in SARS-CoV-2 and other viral infections.
Sarkar L, Liu G, Gack MU. Trends Microbiol. 2023 Dec; 31(12):1262-1275. Epub 2023 Aug 10.

RefSeq genomic sequence
See the genomic reference sequence for the ISG15 gene (NG_033033.2).
RefSeq protein
See the reference protein sequence for ubiquitin-like protein ISG15 (NP_005092.1).

Nucleotide
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MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

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Protein