RecName: Full=Methylated-DNA--protein-cysteine methyltransferase; AltN - Protein

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Variant allelic frequencies of driver mutations can identify gliomas with potentially false-negative MGMT promoter methylation results. [Acta Neuropathol Commun. 2023]
Variant allelic frequencies of driver mutations can identify gliomas with potentially false-negative MGMT promoter methylation results.
McCord M, Jamshidi P, Thirunavu V, Santana-Santos L, Vormittag-Nocito E, Dittman D, Parker S, Baczkowski J, Jennings L, Walshon J, et al. Acta Neuropathol Commun. 2023 Nov 2; 11(1):175. Epub 2023 Nov 2.
Genetic and epigenetic alterations in MGMT gene and correlation with concomitant chemoradiotherapy (CRT) in cervical cancer. [J Cancer Res Clin Oncol. 2023]
Genetic and epigenetic alterations in MGMT gene and correlation with concomitant chemoradiotherapy (CRT) in cervical cancer.
Gupta MK, Kushwah AS, Singh R, Srivastava K, Banerjee M. J Cancer Res Clin Oncol. 2023 Nov; 149(16):15159-15170. Epub 2023 Aug 27.
Significance of O6-methyl guanine methyltransferase promoter methylation in high grade glioma patients: optimal cutoff point, CpG locus, and genetic assay. [J Neurooncol. 2023]
Significance of O6-methyl guanine methyltransferase promoter methylation in high grade glioma patients: optimal cutoff point, CpG locus, and genetic assay.
Buyuktepe M, Kaplan I, Bayatli E, Dogan H, Ugur HC. J Neurooncol. 2023 Aug; 164(1):171-177. Epub 2023 Jul 20.

RefSeq genomic sequence
See the genomic reference sequence for the MGMT gene (NG_052673.1).
RefSeq protein
See the reference protein sequence for methylated-DNA--protein-cysteine methyltransferase (NP_002403.3).

PubMed
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Taxonomy
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BioAssay by Target (Summary)
BioAssay by Target (Summary)
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Identical Structures
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OMIM
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Protein (RefSeq)
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Related Structures (List)
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Related Structures (Summary)
Related structures

P16455 [Domain Mapping of Disease Mut...]
P16455
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

RecName: Full=Methylated-DNA--protein-cysteine methyltransferase; AltName: Full=...
RecName: Full=Methylated-DNA--protein-cysteine methyltransferase; AltName: Full=6-O-methylguanine-DNA methyltransferase; Short=MGMT; AltName: Full=O-6-methylguanine-DNA-alkyltransferase
gi|127069|sp|P16455.1|MGMT_HUMAN

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