RecName: Full=Neuroendocrine convertase 1; Short=NEC 1; AltName: Full= - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.

The N221D variant in PCSK1 is highly prevalent in childhood obesity and can influence the metabolic profile. [J Pediatr Endocrinol Metab. 2023]
The N221D variant in PCSK1 is highly prevalent in childhood obesity and can influence the metabolic profile.
Guijo B, Argente J, Martos-Moreno GÁ. J Pediatr Endocrinol Metab. 2023 Dec 15; 36(12):1140-1145. Epub 2023 Oct 26.
Contribution of heterozygous PCSK1 variants to obesity and implications for precision medicine: a case-control study. [Lancet Diabetes Endocrinol. 2023]
Contribution of heterozygous PCSK1 variants to obesity and implications for precision medicine: a case-control study.
Folon L, Baron M, Toussaint B, Vaillant E, Boissel M, Scherrer V, Loiselle H, Leloire A, Badreddine A, Balkau B, et al. Lancet Diabetes Endocrinol. 2023 Mar; 11(3):182-190.
Rare Heterozygous PCSK1 Variants in Human Obesity: The Contribution of the p.Y181H Variant and a Literature Review. [Genes (Basel). 2022]
Rare Heterozygous PCSK1 Variants in Human Obesity: The Contribution of the p.Y181H Variant and a Literature Review.
Van Dijck E, Beckers S, Diels S, Huybrechts T, Verrijken A, Van Hoorenbeeck K, Verhulst S, Massa G, Van Gaal L, Van Hul W. Genes (Basel). 2022 Sep 27; 13(10). Epub 2022 Sep 27.

RefSeq genomic sequence
See the genomic reference sequence for the PCSK1 gene (NG_021161.1).
RefSeq protein isoforms
See 2 reference sequence protein isoforms for the PCSK1 gene.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioAssay by Target (Summary)
BioAssay by Target (Summary)
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures
Related Structures (Summary)
Related structures

P29120 [Domain Mapping of Disease Mut...]
P29120
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

Your browsing activity is empty.

Activity recording is turned off.

Protein