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- Study Description
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Important Links and Information
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- Data Use Certification (DUC) Agreement
- Talking Glossary of Genetic Terms
We sought to determine the role of ADGRL2 in epidermal homeostasis. Primary neonatal foreskin keratinocytes were obtained from discarded surgical samples at a California hospital. Samples were anonymous and not selected. ADGRL2, working through GNA13, was found to promote epidermal differentiation through the ADGRL2 intracellular loop 3 (ICL3) loop, using the methods of RNA-seq and Perturb-seq.
- Study Design:
- Collection
- Study Type:
- RNA Sequencing
- Transcriptome Analysis
- Total number of consented subjects: 6
- Subject Sample Telemetry Report (SSTR)
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- Publicly Available Data
- Selected Publications
- Diseases/Traits Related to Study (MeSH terms)
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- Primary Phenotype: Epidermis
- Links to Related Genes
- Authorized Data Access Requests
- Study Attribution
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Principal Investigator
- Paul Khavari. Stanford School of Medicine, Palo Alto, CA, USA.
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Sequencing Center
- Novogene Corporation. Sacramento, CA, USA.
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Principal Investigator