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Study Description

The Multi-Ethnic Study of Atherosclerosis (MESA) is a study of the characteristics of subclinical cardiovascular disease (disease detected non-invasively before it has produced clinical signs and symptoms) and the risk factors that predict progression to clinically overt cardiovascular disease or progression of the subclinical disease. MESA researchers study a diverse, population-based sample of 6,814 asymptomatic men and women aged 45-84. Thirty-eight percent of the recruited participants are white, 28 percent African-American, 22 percent Hispanic, and 12 percent Asian, predominantly of Chinese descent.

Electrocardiogram Tracing Repository includes ECG tracings performed during MESA Exam 1 conducted between 2000 and 2002 and during MESA Exam 5 conducted between 2010 and 2012.

Authorized Access
Publicly Available Data
  Link to other NCBI resources related to this study
Study Inclusion/Exclusion Criteria

All MESA participants who attended MESA Exams 1and 5 and consented to the ECG procedure.

Study History

MESA began enrollment July 2000 and completed the baseline examination between 2000 and 2002. Subsequent follow-up Exams 2-7 were completed 2002-2004, 2004-2005, 2005-2007, 2010-2012, 2016-2018, and 2022-2024. Participants were also followed annually for clinical events ascertainment.

Selected Publications
Diseases/Traits Related to Study (MeSH terms)
Authorized Data Access Requests
See research articles citing use of the data from this study
Study Attribution
  • Principal Investigator, ECG Reading Center
    • Elsayed Soliman, MD, MS. Wake Forest University, Winston Salem, NC, USA.
  • Principal Investigator, Coordinating Center
    • Robyn McClelland, PhD. University of Washington, Seattle, WA, USA.
  • Principal Investigator, Field Center
    • Alain Bertoni, MD, MPH. Wake Forest University, Winston Salem, NC, USA.
    • Steven Shea, MD, MS. Columbia University, New York, NY, USA.
    • Wendy Post, MD, MS. Johns Hopkins University, Baltimore, MD, USA.
    • Jim Pankow, PhD, MPH. University of Minnesota, Minneapolis, MN, USA.
    • Norrina Allen, PhD. Northwestern University, Chicago, IL, USA.
    • Karol Watson, MD, PhD. University of California at Los Angeles, Los Angeles, CA, USA.