Jump to: Authorized Access | Attribution | Authorized Requests

Study Description

In this study we developed a high-throughput single-cell DNA methylation analysis technology, sciMETv2. This technique is rapid, cost-effective, and robust, enabling large-scale single-cell methylome dataset generation. We demonstrate this technology on human middle frontal gyrus, where we identified major cell types. We additionally performed target enrichment using sciMET-cap to enable a reduction in sequencing costs per cell while achieving comparable cell type identification.

Authorized Access
Publicly Available Data
  Link to other NCBI resources related to this study
Selected Publications
Diseases/Traits Related to Study (MeSH terms)
Authorized Data Access Requests
Study Attribution
  • Principal Investigator
    • Andrew Adey. Oregon Health and Science University, Portland, OR, USA.
  • Funding Sources
    • Grant R35GM124704. Oregon Health and Science University, Portland, OR, USA.
    • Grant RF1MH128842. Oregon Health and Science University, Portland, OR, USA.