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Study Description

An NCI-funded Cancer Moonshot initiative to construct 3-dimensional atlases of the dynamic cellular, morphological, and molecular features of human cancers as they evolve from precancerous lesions to advanced disease.

  • Study Design:
    • Collection
  • Study Type:
    • Clinical Diagnostic Testing
    • Clinical Genetic Testing
    • Exome Sequencing
    • GWAS
    • Individual-Level Genomic Data
    • Longitudinal
    • Metastasis
    • Methylation Sequencing
    • Multicenter
    • RNA Sequencing
    • Sequencing
    • Single Cell Analysis
    • Tissue Expression
    • Transcriptome Analysis
    • Transcriptome Sequencing
    • Tumor
    • Whole Genome Sequencing
  • Total number of consented subjects: 1349
  • Subject Sample Telemetry Report (SSTR)
Authorized Access
Publicly Available Data
Selected Publications
Diseases/Traits Related to Study (MeSH terms)
Authorized Data Access Requests
Study Attribution
  • Principal Investigators
    • Peter Sorger. Harvard University, Cambridge, MA, USA.
    • Jon Aster. Harvard University, Cambridge, MA, USA.
    • Sandro Santagata. Harvard University, Cambridge, MA, USA.
    • Michael P. Snyder. Stanford University, Stanford, CA, USA.
    • James Ford. Stanford University, Stanford, CA, USA.
    • William Greenleaf. Stanford University, Stanford, CA, USA.
    • Jeremy Goecks. Oregon Health & Science University, Portland, OR, USA.
    • Gordon Mills. Oregon Health & Science University, Portland, OR, USA.
    • George Thomas. Oregon Health & Science University, Portland, OR, USA.
    • Ken S. Lau. Vanderbilt University, Nashville, TN, USA.
    • Robert Coffey. Vanderbilt University, Nashville, TN, USA.
    • Martha Shrubsole. Vanderbilt University, Nashville, TN, USA.
    • Avrum Spira. Boston University, Boston, MA, USA.
    • Steven Dubinett. Boston University, Boston, MA, USA.
    • Kai Tan. Children's Hospital of Philadelphia, Philadelphia, USA.
    • Stephen Hunger. Children's Hospital of Philadelphia, Philadelphia, USA.
    • Bruce Johnson. Dana-Farber Cancer Institute, Boston, MA, USA.
    • Eun-sil (Shelley) Hwang. Duke University, Durham, NC, USA.
    • Carlo Maley. Duke University, Durham, NC, USA.
    • Robert West. Duke University, Durham, NC, USA.
    • Nir Hacohen. Broad Institute of MIT and Harvard, Cambridge, MA, USA.
    • Dana Pe'er. Memorial Sloan Kettering Cancer Center, New York, NY, USA.
    • Christine Iacobuzio-Donahue. Memorial Sloan Kettering Cancer Center, New York, NY, USA.
    • Christopher Amos. Baylor University, Waco, TX, USA.
    • Olivier Harismendy. University of California San Diego, San Diego, CA, USA.
    • Li Ding. Washington University in St. Louis, St. Louis, MO, USA.
    • Ryan Fields. Washington University in St. Louis, St. Louis, MO, USA.
    • William Gillanders. Washington University in St. Louis, St. Louis, MO, USA.
    • Samuel Achilefu. Washington University in St. Louis, St. Louis, MO, USA.