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- Study Description
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Important Links and Information
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Request access via Authorized Access
- Instructions for requestors
- Data Use Certification (DUC) Agreement
- Talking Glossary of Genetic Terms
This analysis represents the genome-wide association study results of several international case-control studies of colorectal cancer.
- Study Design:
- Case-Control
- Study Type:
- Case-Control
- dbGaP estimated ancestry using GRAF-pop
- Total number of consented subjects: 37437
- Subject Sample Telemetry Report (SSTR)
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- Authorized Access
- Publicly Available Data
- Link to other NCBI resources related to this study
- Study Inclusion/Exclusion Criteria
Inclusion Criteria
In general, for cases:
(1) age >18 years (some studies capped age at 69, and others did not),
(2) newly-diagnosed CC (stages I-III),
(3) English or German or Spanish speaking dependent on study locale, and
(4) mentally/physically able to consent and participate.Exclusion Criteria
Pregnant women and prisoners are generally excluded. Each study has specific and detailed control selection criteria, but in general, controls were matched in demographic features to cases and were free of colorectal cancer at the time of selection.- Molecular Data
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Type Source Platform Number of Oligos/SNPs SNP Batch Id Comment Targeted Genotyping Illumina Infinium OncoArray-500k BeadChip N/A N/A - Selected Publications
- Diseases/Traits Related to Study (MeSH terms)
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- Primary Phenotype: Colorectal Neoplasms
- Links to Related Genes
- Authorized Data Access Requests
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See articles in PMC citing this study accession
- Study Attribution
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Principal Investigator
- Stephen B. Gruber, MD, PhD, MPH. City Of Hope, National Cancer Center, Duarte, CA, USA.
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Genotyping Center
- Center for Inherited Disease Research (CIDR). Johns Hopkins University, Baltimore, MD, USA.
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Funding Source for CIDR Genotyping
- HHSN268201200008I, NIH contract "High throughput genotyping for studying the genetic contributions to human disease". National Institutes of Health, Bethesda, MD, USA.
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Principal Investigator