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Study Description

This analysis represents the genome-wide association study results of several international case-control studies of colorectal cancer.

Authorized Access
Publicly Available Data
  Link to other NCBI resources related to this study
Study Inclusion/Exclusion Criteria

Inclusion Criteria
In general, for cases:
(1) age >18 years (some studies capped age at 69, and others did not),
(2) newly-diagnosed CC (stages I-III),
(3) English or German or Spanish speaking dependent on study locale, and
(4) mentally/physically able to consent and participate.

Exclusion Criteria
Pregnant women and prisoners are generally excluded. Each study has specific and detailed control selection criteria, but in general, controls were matched in demographic features to cases and were free of colorectal cancer at the time of selection.

Molecular Data
TypeSourcePlatformNumber of Oligos/SNPsSNP Batch IdComment
Targeted Genotyping Illumina Infinium OncoArray-500k BeadChip N/A N/A
Selected Publications
Diseases/Traits Related to Study (MeSH terms)
Links to Related Genes
Authorized Data Access Requests
See research articles citing use of the data from this study
Study Attribution
  • Principal Investigator
    • Stephen B. Gruber, MD, PhD, MPH. City Of Hope, National Cancer Center, Duarte, CA, USA.
  • Genotyping Center
    • Center for Inherited Disease Research (CIDR). Johns Hopkins University, Baltimore, MD, USA.
  • Funding Source for CIDR Genotyping
    • HHSN268201200008I, NIH contract "High throughput genotyping for studying the genetic contributions to human disease". National Institutes of Health, Bethesda, MD, USA.