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- Study Description
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Important Links and Information
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Request access via Authorized Access
- Instructions for requestors
- Data Use Certification (DUC) Agreement
- Talking Glossary of Genetic Terms
Advances in antiretroviral therapies (ART) and patient management have improved survival of people living with HIV (PLWH). However, with exposure to ART and associated side effects and toxicities as well as to the virus itself, PLWH are at an increased risk of several chronic diseases. The Centers for AIDS Research (CFAR) Network of Integrated Clinical Systems (CNICS) research network integrates longitudinal clinical data and treatment management of PLWH and provides research infrastructure to support HIV-associated clinical, social, and behavioral outcomes and comparative effectiveness research using data collected from 8 Centers for AIDS Research clinical sites across United States. For detailed study description, see Kitahata et al. (2008, PMID:18263650).
- Study Weblinks:
- Study Design:
- Case-Control
- Study Type:
- Longitudinal
- Case-Control
- Cohort
- dbGaP estimated ancestry using GRAF-pop
- Total number of consented subjects: 4761
- Subject Sample Telemetry Report (SSTR)
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Request access via Authorized Access
- Authorized Access
- Publicly Available Data
- Link to other NCBI resources related to this study
- Study Inclusion/Exclusion Criteria
The CNICS cohort includes people living with HIV (PLWH) aged 18 years or older who initiated primary care at one of 8 CNICS sites across the United States, since January 1, 1995. The CNICS repository contains comprehensive clinical and demographic data on PLWH from large and diverse population of participants with regard to sex, race, ethnicity, age, risk factor for HIV transmission and geographic distribution.
- Molecular Data
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Type Source Platform Number of Oligos/SNPs SNP Batch Id Comment Targeted Genotyping BioRealm Smokescreen Genotyping Array N/A N/A - Study History
- Selected Publications
- Diseases/Traits Related to Study (MeSH terms)
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- Primary Phenotype: HIV Infections
- Authorized Data Access Requests
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See articles in PMC citing this study accession
- Study Attribution
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Principal Investigators
- Inga Peter, PhD. Icahn School of Medicine at Mount Sinai, New York, NY, USA.
- Heidi Crane, MD. University of Washington, Seattle, WA, USA.
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CNICS Principal Investigator
- Michael Saag. University of Alabama, Birmingham, AL, USA.
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Funding Source
- R01HL125027. National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
- CNICS R24 AI067039. National Institutes of Health, Bethesda, MD, USA.
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Principal Investigators