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- Study Description
The OPPERA project investigates effects of genetic, physiological, psychological and clinical factors on risk of developing painful temporomandibular disorder. The baseline case-control study evaluated factors associated with chronic temporomandibular disorder among OPPERA participants who enrolled in the study between May 2006 and November 2008.
- Authorized Access
- Publicly Available Data (Public ftp)
- Study Inclusion/Exclusion Criteria
Inclusion criteria were all three of:
- Age 18-44 years
- Planning on living in the area for the next two years
- Fluent in written and spoken English.
Exclusion criteria were any one of 13 conditions:
- Traumatic facial injury or surgery on the face or jaw within the six months preceding enrollment
- Currently receiving orthodontic treatment
- Pregnant or nursing
- Kidney failure or renal dialysis
- Heart disease or heart failure
- Chronic respiratory disease that is not controlled with medication
- Hypertension that is not controlled with medication
- Epilepsy or medication to control grand mal seizures
- Diabetes that is not controlled with medication or diet
- Drug or alcohol abuse
- Psychiatric disorders or conditions that have required hospitalization
- Chemotherapy or radiation therapy.
- Molecular Data
Type Source Platform Number of Oligos/SNPs SNP Batch Id Comment Targeted Genotyping Algynomics Algynomics Pain Research Panel N/A N/A
- Study History
The OPPERA project began in 2006 with enrollment of participants into two studies at four U.S. study sites: Baltimore, MD; Buffalo, NY; Chapel Hill, NC; and Gainesville, FL. In 2012, the National Institute of Dental and Craniofacial Research (NIDCR) awarded funding to support the study for an additional five year period.
- Selected publications
- Diseases/Traits Related to Study (MeSH terms)
- Links to Related Resources
- Authorized Data Access Requests
See research articles citing use of the data from this study
- Study Attribution