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Lung carcinoma is the leading cause of cancer death in the United States and world-wide; lung adenocarcinoma is the most common cause of lung cancer. Pilot studies of lung adenocarcinoma with hybrid-capture based whole exome sequencing will enable us to identify new targets for therapy and improve diagnosis. We will analyze a blend of whole exome and whole genome sequencing data as well as copy number and somatic mutation calls for 200 tumor and matched normal controls. When completed this study will represent the most comprehensive lung adenocarcinoma genome dataset to date.
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- Case Set
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- Molecular Data
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Type Source Platform Number of Oligos/SNPs SNP Batch Id Comment Whole Exome Sequencing Agilent Agilent selected, 76bp paired end reads N/A N/A Whole Genome Sequencing Illumina 101bp paired end reads N/A N/A Whole Genome Genotyping Affymetrix AFFY_6.0 934940 52074 - Selected publications
- Diseases/Traits Related to Study (MeSH terms)
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- Primary Phenotype: Carcinoma, Non-Small-Cell Lung
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