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Study Description

The goal of the project is to identify genes that make individuals more susceptible to bipolar disorder (manic depressive illness) and to better understand the brain pathways involved in the disease.

Dataset versioning

  • Version 1: European-American (EA) ancestry only
  • Version 2: Version 1 plus African-American (AA) ancestry
  • Version 3: EA and AA samples plus updated diagnostic criteria

Consent groups and participant set

  • General research use (GRU): 1767 controls (1081 EA controls, 686 AA controls)
    This consent group includes all controls for the Bipolar study, which are a subset of controls for the Schizophrenia study (subset of Schizophrenia: GRU).
  • Bipolar and related disorders (BARD): 841 cases (691 EA cases, 150 AA cases)
    This consent group includes a subset of the Bipolar cases.
  • Bipolar disorder only (BDO): 653 cases (388 EA cases, 265 AA cases)
    This consent group includes a subset of the Bipolar cases.

Authorized Access
Publicly Available Data (Public ftp)

Connect to the public download site. The site contains release notes and manifests. If available, the site also contains data dictionaries, variable summaries, documents, and truncated analyses.

Molecular Data
TypeSourcePlatformNumber of Oligos/SNPsSNP Batch IdComment
Whole Genome Genotyping Affymetrix AFFY_6.0 934940 52074
Selected publications
Diseases/Traits Related to Study (MESH terms)
Links to Related Resources
Authorized Data Access Requests
Study Attribution