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Reference SNP (refSNP) Cluster Report: rs16922827                 
RefSNP
Organism:human (Homo sapiens)
Molecule Type:Genomic
Created/Updated in build:123/151
Map to Genome Build:108/Weight 1
Validation Status:byClusterbyFreqWith1000GenomeData
Allele
Variation Class:SNV:
single nucleotide variation
RefSNP Alleles:G/T (FWD)
Allele Origin:
Ancestral Allele:T
Variation Viewer:link to VariationViewer
Clinical Significance:NA
MAF/MinorAlleleCount:G=0.1230/616 (1000 Genomes)
G=0.0940/11809 (TOPMED)
HGVS Names
  • CM000672.2:g.66325595T>G
  • NC_000010.10:g.68085353T>G
  • NC_000010.11:g.66325595T>G
  • NG_034072.1:g.1375597A>C
  • NM_001127384.2:c.1733-44974A>C
  • NM_013266.3:c.1733-44974A>C
Links , Linkout
SNP Details are organized in the following sections:
GeneView Map Submission Fasta Resource Diversity Validation

  Integrated Maps (Hint: click on 'Chr Pos' to see variant in the new NCBI variation viewer) back to top

  GeneView back to top

GeneView via direct blast against RefSeq sequences (used when no gene model is available): N/A


  Submitter records for this RefSNP Cluster back to top
The submission ss280656693 has the longest flanking sequence of all cluster members and was used to instantiate sequence for rs16922827 during BLAST analysis for the current build.


NCBI
Assay ID
Handle|Submitter IDValidation
Status
ss to rs
Orientation
/Strand
Alleles5' Near Seq 30 bp3' Near Seq 30 bpEntry
Date
Update
Date
Build
Added
Molecule
Type
Freq
Warning
Ancestral
Allele
Success
Rate
ss24060089PERLEGEN|afd2262899byFreqfwd/BG/Tttgttttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttctacatct08/10/0409/13/04123Genomicunknown
ss66831460ILLUMINA|HumanHap300v1.1_rs16922827fwd/TG/Tttgttttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttctacatct11/09/0611/09/06127Genomicunknown
ss67157357ILLUMINA|HumanHap550v1.1_rs16922827fwd/BG/Tttgttttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttctacatct11/14/0611/14/06127Genomicunknown
ss67504865ILLUMINA|HumanHap650Yv1.0_rs16922827fwd/BG/Tttgttttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttctacatct11/14/0611/14/06127Genomicunknown
ss70448928ILLUMINA|HumanHap300v2.0_rs16922827fwd/BG/Tttgttttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttctacatct04/18/0711/18/07127Genomicunknown
ss70644706ILLUMINA|HumanHap550v3.0__rs16922827rev/TA/Cagatgtagaacaggtgagcatcttcctcagacaacccttcattgtcttcattgaaaacaa04/20/0703/30/08130Genomicunknown
ss71198560ILLUMINA|HumanHap650Yv3.0_rs16922827fwd/BG/Tttgttttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttctacatct04/23/0704/23/07127Genomicunknown
ss74828467AFFY|SNP_M-584834fwd/BG/Tttgttttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttctacatct08/09/0708/09/07128Genomicunknown
ss75870127ILLUMINA|ILMN_Human_1M_rs16922827fwd/BG/Tttgttttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttctacatct08/28/0708/29/07129Genomicunknown
ss85336843KRIBB_YJKIM|KHS967943fwd/BG/Tttgttttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttctacatct12/04/0712/09/07130Genomicunknown
ss121778250ILLUMINA|HumanCNV370v1_C_rs16922827fwd/BG/Tttgttttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttctacatct04/14/0904/14/09131Genomicunknown
ss153577776ILLUMINA|Human610_Quadv1_B_rs16922827-128_T_R_1501679365rev/TA/Cagatgtagaacaggtgagcatcttcctcagacaacccttcattgtcttcattgaaaacaa06/18/0906/19/09131Genomicunknown
ss159297731ILLUMINA|Human660W-Quad_v1_A_rs16922827-128_T_R_1501679365rev/TA/Cagatgtagaacaggtgagcatcttcctcagacaacccttcattgtcttcattgaaaacaa07/06/0907/06/09131Genomicunknown
ss160397362ILLUMINA|HumanOmni1-Quad_v1-0_B_rs16922827-128_T_R_1501679365rev/TA/Cagatgtagaacaggtgagcatcttcctcagacaacccttcattgtcttcattgaaaacaa08/04/0910/02/09131Genomicunknown
ss170723168ILLUMINA|HumanCNV370-Quadv3_C_rs16922827-128_T_R_1501679365rev/TA/Cagatgtagaacaggtgagcatcttcctcagacaacccttcattgtcttcattgaaaacaa10/01/0910/03/09132Genomicunknown
ss172662758ILLUMINA|Human1M-Duov3_B_rs16922827-128_T_R_1501679365rev/TA/Cagatgtagaacaggtgagcatcttcctcagacaacccttcattgtcttcattgaaaacaa10/01/0910/02/09132Genomicunknown
ss2247799321000GENOMES|pilot_1_YRI_6589615_chr10_67755359fwd/G/Tttgttttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttctacatct04/22/1004/22/10132Genomicunknown
ss2352159121000GENOMES|pilot_1_CEU_4820541_chr10_67755359fwd/G/Tttgttttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttctacatct05/01/1005/01/10132Genomicunknown
ss2419138281000GENOMES|pilot_1_CHB+JPT_3798905_chr10_67755359fwd/G/Tttgttttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttctacatct05/01/1005/01/10132Genomicunknown
ss280656693GMI|GMI_AK_SNP_4977028fwd/G/Tttgttttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttctacatct12/16/1012/16/10137Genomicunknown
ss410910018ILLUMINA|Cardio-Metabo_Chip_11395247_A_rs16922827rev/TA/Cagatgtagaacaggtgagcatcttcctcagacaacccttcattgtcttcattgaaaacaa06/07/1106/07/11135Genomicunknown
ss480105467ILLUMINA|HumanOmni2.5-4v1_B_rs16922827-128_T_R_1766538628fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta01/30/1210/28/16137Genomicunknown
ss480114350ILLUMINA|HumanOmniExpress-12v1_C_rs16922827-131_T_R_1857667416fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta01/30/1210/27/16137Genomicunknown
ss480806409ILLUMINA|HumanOmni1-Quad_v1-0_C_rs16922827-131_T_R_1865363393fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta01/30/1208/28/15146Genomicunknown
ss484850589ILLUMINA|HumanOmni2.5-4v1_D_rs16922827-131_T_R_1857667416fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta01/30/1210/27/16137Genomicunknown
ss491435908EXOME_CHIP|.GWAS._152134_chr_10_68085353fwd/BG/Tttgttttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttctacatct03/05/1203/05/12137Genomicunknown
ss536919763ILLUMINA|HumanOmni5-4v1_B_rs16922827-131_T_R_1885473830fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta06/22/1208/29/15146Genomicunknown
ss562017159TISHKOFF|snp_chr10_68085353fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta11/22/1211/23/12138Genomicunknown
ss656883528SSMP|10_68085353fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta12/14/1202/12/15138Genomicunknown
ss778446486ILLUMINA|HumanOmni25Exome-8v1_A_rs16922827-131_T_R_1865363393fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta05/30/1307/10/15146Genomicunknown
ss780682259ILLUMINA|HumanOmni25Exome-8v1_A_exm-rs16922827-131_T_R_1990489044fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta05/30/1307/10/15146Genomicunknown
ss782871809ILLUMINA|HumanOmni2.5-4v1_H_rs16922827-131_T_R_1857667416fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta05/30/1307/29/15146Genomicunknown
ss783355604ILLUMINA|HumanOmniExpressExome-8v1_A_exm-rs16922827-131_T_R_1990489044fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta05/31/1306/18/15146Genomicunknown
ss783835853ILLUMINA|HumanOmniExpressExome-8v1_A_rs16922827-131_T_R_1885473830fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta05/31/1306/18/15146Genomicunknown
ss825417661ILLUMINA|HumanCNV370v1_C_rs16922827-123_T_R_IFB1137779300:0fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta06/24/1311/21/14144Genomicunknown
ss832125989ILLUMINA|HumanOmniExpress-12v1_H_rs16922827-131_T_R_1857667416fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta09/17/1306/18/15146Genomicunknown
ss833902061ILLUMINA|HumanOmni2.5-8v1_A_rs16922827-131_T_R_1865363393fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta09/18/1307/29/15146Genomicunknown
ss987592206EVA-GONL|EVA-GONL_rs16922827fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta04/23/1404/25/14142Genomicunknown
ss1077064738JMKIDD_LAB|HGDP_WGS_chr10_68085353fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta07/10/1407/11/14142Genomicunknown
ss13378259771000GENOMES|PHASE3_V1_50495439fwd/G/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta08/16/1408/16/14142Genomicunknown
ss1426352077DDI|DDI_rs16922827fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta11/04/1411/04/14144Genomicunknown
ss1575179339EVA_GENOME_DK|EVA_GENOME_DK_snv_rs16922827fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta02/19/1502/19/15144Genomicunknown
ss1597261821EVA_DECODE|EVA_DECODE_10_67755359_517806_rs16922827fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta03/02/1503/03/15144Genomicunknown
ss1624771442EVA_UK10K_ALSPAC|EVA_UK10K_ALSPAC_10_68085353_27878986fwd/G/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta03/04/1503/04/15144Genomicunknown
ss1667765475EVA_UK10K_TWINSUK|EVA_UK10K_TWINSUK_10_68085353_27878986fwd/G/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta03/04/1503/04/15144Genomicunknown
ss1713186783EVA_SVP|EVA_SVP_881150fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta03/12/1503/12/15144Genomicunknown
ss1751976705ILLUMINA|OmniExpressExome-8v1-1_B_exm-rs16922827-131_T_R_1990489044fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta05/27/1506/09/15146Genomicunknown
ss1751976706ILLUMINA|OmniExpressExome-8v1-1_B_rs16922827-131_T_R_1885473830fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta05/27/1506/09/15146Genomicunknown
ss1917847443ILLUMINA|HumanExome-12v1-1_B_exm-rs16922827-131_T_R_1990489044fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta10/16/1510/16/15147Genomicunknown
ss1930955518WEILL_CORNELL_DGM|SNV:chr10:68085353fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta10/16/1510/17/15147Genomicunknown
ss1946284292ILLUMINA|HumanCoreExome-12v1-0_C_exm-rs16922827-131_T_R_1990489044fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta10/29/1510/29/15147Genomicunknown
ss1959269218ILLUMINA|exm-rs16922827-131_T_R_1990489044fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta11/13/1511/13/15147Genomicunknown
ss1967153433GENOMED|rs16922827fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta02/16/1602/16/16147Genomicunknown
ss2026203214JJLAB|SNP6705769fwd/BG/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta08/29/1608/30/16149Genomicunknown
ss2154476027USC_VALOUEV|NC_000010.10:g.68085353T>Gfwd/G/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta11/17/1611/17/16150Genomicunknown
ss2175546923HUMAN_LONGEVITY|HLI-10-66325595-T-Gfwd/G/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta11/18/1611/18/16150Genomicunknown
ss2338583397TOPMED|10_68085353_T/Gfwd/G/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta11/19/1611/19/16150Genomicunknown
ss2627571389SYSTEMSBIOZJU|SYSTEMSBIOZJU_SNV4252210fwd/G/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta01/06/1701/06/17151Genomicunknown
ss2632722500ILLUMINA|SoL_HCHS_Custom_15041502_B3_RefStrand_rs16922827-131_T_R_1885473fwd/G/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta02/02/1702/02/17151Genomicunknown
ss2698720935GRF|rs16922827fwd/G/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta02/13/1702/13/17151Genomicunknown
ss2889871466GNOMAD|rs16922827fwd/G/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta05/19/1705/19/17151Genomicunknown
ss2984913959AFFY|Axiom_PsorMich_Affx-3531724fwd/G/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta05/24/1705/24/17151Genomicunknown
ss3006637174SWEGEN|NC_000010.10:g.68085353T>Gfwd/G/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta05/30/1705/30/17151Genomicunknown
ss3021247386ILLUMINA|MEGA_Consortium_v2_15070954_A2_exm-rs16922827-131_T_R_1990489044fwd/G/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta06/28/1706/28/17151Genomicunknown
ss3026892927BIOINF_KMB_FNS_UNIBA|10.66325595T>Gfwd/G/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta07/05/1707/05/17151Genomicunknown
ss3122350038TOPMED|TOPMed_freeze_5?chr10:66,325,595fwd/G/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta09/29/1709/29/17151Genomicunknown
ss3349168918CSHL|rs16922827fwd/G/Tttcaatgaagacaatgaagggttgtctgaggaagatgctcacctgttcta10/02/1710/02/17151Genomicunknown

  Fasta sequence   (Legend) back to top
>gnl|dbSNP|rs16922827|allelePos=501|totalLen=1001|taxid=9606|snpclass=1|alleles='G/T'|mol=Genomic|build=151
 TCCCCATGAG TCTTTTGGGA CCAAAAGCAA ACATTAAAAT AAGAATAGGC ACACGAAAGG
 CAGGAGTGCA AATACACTTA ACGATAATCA GTAATGACTG TAGTCCCTCA GCTACATGCT
 TATCAGTTTT TGTTTAGTAT TGACTGTTTT CTGTACATTA AAGGGTGAAA GAAAAAGAAA
 CATTAAAAAT GTGCTGGGTA CCTTCTATGT GCAAAACTTT GAATGACAGA TTTGATTTTA
 CCATTTCAAA GAATAGAAAC TAGCAAACAA GAGTCAAGAT GAGTTGTTCA TATCTTGCCT
 GCAGAAAAAA TAACGTGCTT CTTTTTGTTG TAGAGCCGAG GAGTCTCCCT ATGTTGCCCA
 AGGTGGTCTT GAACTCCTAG GCTCAAGGGA TCCTCCTGCC TTGATCTCTG AAAGTGCTGG
 GATTATAGGC ATGAGCCGCT GCACCTGGCC AACAATGAGC TTCTTAATAA TTGTTTTCAA
 TGAAGACAAT GAAGGGTTGT
 K
 CTGAGGAAGA TGCTCACCTG TTCTACATCT CCCCTGCAAG CAAATCTAAA GGCAAAGAGT
 GCAGCTCTAA CCAAGTCATA AGGCATGCCT TCTTGACTCT GAGGCTGTTT AGCCACAAGA
 ACTACCAAGG GACTCTAAGT GGGGTCCTGC TATTAGAAAC ATTAAATCTA GGACTGAAAA
 TTGTCTGTTT GAAATAGTTA TGTGCTCATA TTAAAAAATG AGAACTGATT AGGTAAATTG
 GGAGAGCAAA AGGGCAAGAC AATGTCTGTT ATTGATGATT TTCAGATTGC TGAATTAAAA
 TGCTTATTTC ATTCGAGAAG AAGGATTTAA CAGCCAAAAT CACACTTAAC CATGCATGAA
 AAGAGCCACT GTTGAAAAAT GGCTGATAAA AATGATTACT CAATTTTAAA AGCCTGCATT
 GTTTAACGTA ATTGATGCAA ACTTTAGAGA ACTGAGTCAG AATTTTGTAA AATGAACAAG
 CTCAATCCAA CTAATACAAG

  NCBI Resource Links back to top
Submitter-Referenced
GenBank
NC_000010.5
dbSNP Blast Analysis

  Population Diversity (Alleles in RefSNP orientation) . See additional population frequency from 1000Genome [here] back to top

Sample AscertainmentGenotype DetailAlleles
ss#PopulationIndividual
Group
Chrom.
Sample Cnt.
SourceG/G
G/T
T/T
HWPG
T
ss1337825977EAS 1008AF 0.224200010.77579999
EUR 1006AF 0.116300000.88370001
AFR 1322AF 0.025700000.97430003
AMR 694AF 0.157099990.84289998
SAS 978AF 0.132900000.86710000
ss224779932pilot_1_YRI_low_coverage_panel 118AF 0.008474580.99152541
ss235215912pilot_1_CEU_low_coverage_panel 120AF 0.100000000.89999998
ss24060089AFD_EUR_PANELEuropean 48IG 0.166666670.833333311.000000000.083333340.91666669
AFD_AFR_PANELAfrican American 46IG0.04347826 0.956521750.001000000.043478260.95652175
AFD_CHN_PANELAsian 48IG0.041666670.333333340.625000001.000000000.208333330.79166669
HapMap-CEUEuropean 224IG0.017857140.178571430.803571400.527089000.107142860.89285713
HapMap-HCBAsian 84IG0.071428570.357142870.571428601.000000000.250000000.75000000
HapMap-JPTAsian 170IG0.047058820.435294120.517647090.294266000.264705900.73529410
HapMap-YRISub-Saharan African 222IG 0.045045040.954954981.000000000.022522520.97747749
HAPMAP-ASW 98IG 0.040816330.959183691.000000000.020408160.97959185
HAPMAP-CHBAsian 82IG0.097560970.365853670.536585390.583882000.280487810.71951222
HAPMAP-CHD 168IG0.059523810.273809520.666666690.250592000.196428570.80357140
HAPMAP-GIH 172IG 0.174418600.825581370.751830000.087209300.91279072
HAPMAP-LWK 176IG 0.034090910.965909061.000000000.017045460.98295456
HAPMAP-MEX 100IG 0.239999990.759999990.654721000.120000000.88000000
HAPMAP-MKK 286IG0.020979020.132867130.846153860.050043000.087412590.91258740
HAPMAP-TSI 176IG0.011363640.227272730.761363630.751830000.125000000.87500000
ss241913828pilot_1_CHB+JPT_low_coverage_panel 120AF 0.216666670.78333336

SummaryAverage
Het.+/- std err:
Individual
Count
Founders
Count
Individual
Overlap
Genotype
Conflict
Additional Freq. Data
0.216+/-0.2480000ALFRED: The Allele Frequency Database

  Validation Summary: back to top
Validation statusMarker displays
Mendelian segregation
PCR results confirmed
in multiple reactions
Homozygotes detected
in individual genotype data
byClusterbyFreqWith1000GenomeDataUNKNOWNUNKNOWNUNKNOWN

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