Name: rs677909
Published: September 21, 2022
License: Open Access

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs677909

Current Build 156

Released September 21, 2022

Organism: Homo sapiens
Position: chr11:86046547 (GRCh38.p14) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
Alleles: C>T
Variation Type: SNV Single Nucleotide Variation
Frequency: C=0.278896 (73821/264690, TOPMED)
C=0.275701 (38586/139956, GnomAD)
C=0.31662 (22829/72102, ALFA) (+ 19 more)
C=0.43351 (12250/28258, 14KJPN)
C=0.43030 (7211/16758, 8.3KJPN)
C=0.2976 (1906/6404, 1000G_30x)
C=0.3041 (1523/5008, 1000G)
C=0.3183 (1426/4480, Estonian)
C=0.3220 (1241/3854, ALSPAC)
C=0.3099 (1149/3708, TWINSUK)
C=0.3898 (1142/2930, KOREAN)
C=0.4052 (838/2068, HGDP_Stanford)
C=0.2534 (478/1886, HapMap)
C=0.3941 (722/1832, Korea1K)
C=0.310 (309/998, GoNL)
C=0.348 (209/600, NorthernSweden)
C=0.249 (111/446, SGDP_PRJ)
C=0.394 (85/216, Qatari)
C=0.407 (87/214, Vietnamese)
C=0.28 (16/58, Ancient Sardinia)
C=0.26 (13/50, Siberian)
C=0.33 (13/40, GENOME_DK)

Clinical Significance: Not Reported in ClinVar
Gene : Consequence: PICALM : Intron Variant
LOC124902730 : Non Coding Transcript Variant
Publications: 2 citations
Genomic View: See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20230706150541

Population	Group	Sample Size	Ref Allele	Alt Allele
Total	Global	72102	C=0.31662	T=0.68338
European	Sub	56078	C=0.32294	T=0.67706
African	Sub	5144	C=0.1320	T=0.8680
African Others	Sub	182	C=0.093	T=0.907
African American	Sub	4962	C=0.1334	T=0.8666
Asian	Sub	232	C=0.362	T=0.638
East Asian	Sub	158	C=0.361	T=0.639
Other Asian	Sub	74	C=0.36	T=0.64
Latin American 1	Sub	390	C=0.292	T=0.708
Latin American 2	Sub	3364	C=0.3915	T=0.6085
South Asian	Sub	4888	C=0.3818	T=0.6182
Other	Sub	2006	C=0.3285	T=0.6715

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

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Study	Population	Group	Sample Size	Ref Allele	Alt Allele
TopMed	Global	Study-wide	264690	C=0.278896	T=0.721104
gnomAD - Genomes	Global	Study-wide	139956	C=0.275701	T=0.724299
gnomAD - Genomes	European	Sub	75800	C=0.32544	T=0.67456
gnomAD - Genomes	African	Sub	41936	C=0.14005	T=0.85995
gnomAD - Genomes	American	Sub	13626	C=0.36350	T=0.63650
gnomAD - Genomes	Ashkenazi Jewish	Sub	3320	C=0.3693	T=0.6307
gnomAD - Genomes	East Asian	Sub	3124	C=0.4014	T=0.5986
gnomAD - Genomes	Other	Sub	2150	C=0.2847	T=0.7153
Allele Frequency Aggregator	Total	Global	72102	C=0.31662	T=0.68338
Allele Frequency Aggregator	European	Sub	56078	C=0.32294	T=0.67706
Allele Frequency Aggregator	African	Sub	5144	C=0.1320	T=0.8680
Allele Frequency Aggregator	South Asian	Sub	4888	C=0.3818	T=0.6182
Allele Frequency Aggregator	Latin American 2	Sub	3364	C=0.3915	T=0.6085
Allele Frequency Aggregator	Other	Sub	2006	C=0.3285	T=0.6715
Allele Frequency Aggregator	Latin American 1	Sub	390	C=0.292	T=0.708
Allele Frequency Aggregator	Asian	Sub	232	C=0.362	T=0.638
14KJPN	JAPANESE	Study-wide	28258	C=0.43351	T=0.56649
8.3KJPN	JAPANESE	Study-wide	16758	C=0.43030	T=0.56970
1000Genomes_30x	Global	Study-wide	6404	C=0.2976	T=0.7024
1000Genomes_30x	African	Sub	1786	C=0.0890	T=0.9110
1000Genomes_30x	Europe	Sub	1266	C=0.3136	T=0.6864
1000Genomes_30x	South Asian	Sub	1202	C=0.4168	T=0.5832
1000Genomes_30x	East Asian	Sub	1170	C=0.3897	T=0.6103
1000Genomes_30x	American	Sub	980	C=0.401	T=0.599
1000Genomes	Global	Study-wide	5008	C=0.3041	T=0.6959
1000Genomes	African	Sub	1322	C=0.0953	T=0.9047
1000Genomes	East Asian	Sub	1008	C=0.4008	T=0.5992
1000Genomes	Europe	Sub	1006	C=0.3191	T=0.6809
1000Genomes	South Asian	Sub	978	C=0.409	T=0.591
1000Genomes	American	Sub	694	C=0.392	T=0.608
Genetic variation in the Estonian population	Estonian	Study-wide	4480	C=0.3183	T=0.6817
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.3220	T=0.6780
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.3099	T=0.6901
KOREAN population from KRGDB	KOREAN	Study-wide	2930	C=0.3898	T=0.6102
HGDP-CEPH-db Supplement 1	Global	Study-wide	2068	C=0.4052	T=0.5948
HGDP-CEPH-db Supplement 1	Est_Asia	Sub	464	C=0.420	T=0.580
HGDP-CEPH-db Supplement 1	Central_South_Asia	Sub	414	C=0.399	T=0.601
HGDP-CEPH-db Supplement 1	Middle_Est	Sub	348	C=0.399	T=0.601
HGDP-CEPH-db Supplement 1	Europe	Sub	316	C=0.396	T=0.604
HGDP-CEPH-db Supplement 1	Africa	Sub	242	C=0.107	T=0.893
HGDP-CEPH-db Supplement 1	America	Sub	212	C=0.708	T=0.292
HGDP-CEPH-db Supplement 1	Oceania	Sub	72	C=0.53	T=0.47
HapMap	Global	Study-wide	1886	C=0.2534	T=0.7466
HapMap	American	Sub	768	C=0.339	T=0.661
HapMap	African	Sub	690	C=0.086	T=0.914
HapMap	Asian	Sub	252	C=0.421	T=0.579
HapMap	Europe	Sub	176	C=0.301	T=0.699
Korean Genome Project	KOREAN	Study-wide	1832	C=0.3941	T=0.6059
Genome of the Netherlands Release 5	Genome of the Netherlands	Study-wide	998	C=0.310	T=0.690
Northern Sweden	ACPOP	Study-wide	600	C=0.348	T=0.652
SGDP_PRJ	Global	Study-wide	446	C=0.249	T=0.751
Qatari	Global	Study-wide	216	C=0.394	T=0.606
A Vietnamese Genetic Variation Database	Global	Study-wide	214	C=0.407	T=0.593
Ancient Sardinia genome-wide 1240k capture data generation and analysis	Global	Study-wide	58	C=0.28	T=0.72
Siberian	Global	Study-wide	50	C=0.26	T=0.74
The Danish reference pan genome	Danish	Study-wide	40	C=0.33	T=0.68

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements

Sequence name	Change
GRCh38.p14 chr 11	NC_000011.10:g.86046547C>T
GRCh37.p13 chr 11	NC_000011.9:g.85757589C>T
PICALM RefSeqGene	NG_028942.1:g.28335G>A

Gene: PICALM, phosphatidylinositol binding clathrin assembly protein (minus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
PICALM transcript variant 2	NM_001008660.3:c.131-1493… NM_001008660.3:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant 3	NM_001206946.2:c.131-1493… NM_001206946.2:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant 4	NM_001206947.2:c.-23-1493… NM_001206947.2:c.-23-14936G>A	N/A	Intron Variant
PICALM transcript variant 1	NM_007166.4:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X1	XM_005274322.4:c.131-1493… XM_005274322.4:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X2	XM_005274326.4:c.131-1493… XM_005274326.4:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X3	XM_005274328.4:c.131-1493… XM_005274328.4:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X6	XM_005274329.5:c.131-1493… XM_005274329.5:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X9	XM_005274331.4:c.131-1493… XM_005274331.4:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X9	XM_005274334.4:c.131-1493… XM_005274334.4:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X12	XM_005274336.4:c.131-1493… XM_005274336.4:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X15	XM_005274337.4:c.131-1493… XM_005274337.4:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X22	XM_005274340.4:c.131-1493… XM_005274340.4:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X5	XM_017018381.3:c.131-1493… XM_017018381.3:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X13	XM_017018383.3:c.131-1493… XM_017018383.3:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X14	XM_017018384.3:c.131-1493… XM_017018384.3:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X16	XM_017018385.3:c.131-1493… XM_017018385.3:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X18	XM_017018386.3:c.131-1493… XM_017018386.3:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X19	XM_017018387.3:c.131-1493… XM_017018387.3:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X20	XM_017018388.3:c.131-1493… XM_017018388.3:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X4	XM_024448700.2:c.131-1493… XM_024448700.2:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X7	XM_047427659.1:c.131-1493… XM_047427659.1:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X8	XM_047427660.1:c.-23-1493… XM_047427660.1:c.-23-14936G>A	N/A	Intron Variant
PICALM transcript variant X10	XM_047427661.1:c.131-1493… XM_047427661.1:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X11	XM_047427662.1:c.131-1493… XM_047427662.1:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X17	XM_047427663.1:c.131-1493… XM_047427663.1:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X21	XM_047427665.1:c.131-1493… XM_047427665.1:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X23	XM_047427666.1:c.-23-1493… XM_047427666.1:c.-23-14936G>A	N/A	Intron Variant
PICALM transcript variant X24	XM_047427667.1:c.131-1493… XM_047427667.1:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X25	XM_047427668.1:c.131-1493… XM_047427668.1:c.131-14936G>A	N/A	Intron Variant
PICALM transcript variant X26	XM_047427669.1:c.131-1493… XM_047427669.1:c.131-14936G>A	N/A	Intron Variant

Gene: LOC124902730, uncharacterized LOC124902730 (minus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
LOC124902730 transcript variant X1	XR_007062822.1:n.17330G>A	N/A	Non Coding Transcript Variant

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement	C=	T
GRCh38.p14 chr 11	NC_000011.10:g.86046547=	NC_000011.10:g.86046547C>T
GRCh37.p13 chr 11	NC_000011.9:g.85757589=	NC_000011.9:g.85757589C>T
PICALM RefSeqGene	NG_028942.1:g.28335=	NG_028942.1:g.28335G>A
LOC124902730 transcript variant X1	XR_007062822.1:n.17330=	XR_007062822.1:n.17330G>A
PICALM transcript variant 2	NM_001008660.2:c.131-14936=	NM_001008660.2:c.131-14936G>A
PICALM transcript variant 2	NM_001008660.3:c.131-14936=	NM_001008660.3:c.131-14936G>A
PICALM transcript variant 3	NM_001206946.1:c.131-14936=	NM_001206946.1:c.131-14936G>A
PICALM transcript variant 3	NM_001206946.2:c.131-14936=	NM_001206946.2:c.131-14936G>A
PICALM transcript variant 4	NM_001206947.1:c.-23-14936=	NM_001206947.1:c.-23-14936G>A
PICALM transcript variant 4	NM_001206947.2:c.-23-14936=	NM_001206947.2:c.-23-14936G>A
PICALM transcript variant 1	NM_007166.3:c.131-14936=	NM_007166.3:c.131-14936G>A
PICALM transcript variant 1	NM_007166.4:c.131-14936=	NM_007166.4:c.131-14936G>A
PICALM transcript variant X1	XM_005274322.1:c.131-14936=	XM_005274322.1:c.131-14936G>A
PICALM transcript variant X1	XM_005274322.4:c.131-14936=	XM_005274322.4:c.131-14936G>A
PICALM transcript variant X2	XM_005274323.1:c.131-14936=	XM_005274323.1:c.131-14936G>A
PICALM transcript variant X3	XM_005274324.1:c.131-14936=	XM_005274324.1:c.131-14936G>A
PICALM transcript variant X4	XM_005274325.1:c.131-14936=	XM_005274325.1:c.131-14936G>A
PICALM transcript variant X5	XM_005274326.1:c.131-14936=	XM_005274326.1:c.131-14936G>A
PICALM transcript variant X2	XM_005274326.4:c.131-14936=	XM_005274326.4:c.131-14936G>A
PICALM transcript variant X6	XM_005274327.1:c.131-14936=	XM_005274327.1:c.131-14936G>A
PICALM transcript variant X7	XM_005274328.1:c.131-14936=	XM_005274328.1:c.131-14936G>A
PICALM transcript variant X3	XM_005274328.4:c.131-14936=	XM_005274328.4:c.131-14936G>A
PICALM transcript variant X8	XM_005274329.1:c.131-14936=	XM_005274329.1:c.131-14936G>A
PICALM transcript variant X6	XM_005274329.5:c.131-14936=	XM_005274329.5:c.131-14936G>A
PICALM transcript variant X9	XM_005274330.1:c.131-14936=	XM_005274330.1:c.131-14936G>A
PICALM transcript variant X10	XM_005274331.1:c.131-14936=	XM_005274331.1:c.131-14936G>A
PICALM transcript variant X9	XM_005274331.4:c.131-14936=	XM_005274331.4:c.131-14936G>A
PICALM transcript variant X11	XM_005274332.1:c.131-14936=	XM_005274332.1:c.131-14936G>A
PICALM transcript variant X12	XM_005274333.1:c.131-14936=	XM_005274333.1:c.131-14936G>A
PICALM transcript variant X13	XM_005274334.1:c.131-14936=	XM_005274334.1:c.131-14936G>A
PICALM transcript variant X9	XM_005274334.4:c.131-14936=	XM_005274334.4:c.131-14936G>A
PICALM transcript variant X14	XM_005274335.1:c.131-14936=	XM_005274335.1:c.131-14936G>A
PICALM transcript variant X15	XM_005274336.1:c.131-14936=	XM_005274336.1:c.131-14936G>A
PICALM transcript variant X12	XM_005274336.4:c.131-14936=	XM_005274336.4:c.131-14936G>A
PICALM transcript variant X16	XM_005274337.1:c.131-14936=	XM_005274337.1:c.131-14936G>A
PICALM transcript variant X15	XM_005274337.4:c.131-14936=	XM_005274337.4:c.131-14936G>A
PICALM transcript variant X19	XM_005274340.1:c.131-14936=	XM_005274340.1:c.131-14936G>A
PICALM transcript variant X22	XM_005274340.4:c.131-14936=	XM_005274340.4:c.131-14936G>A
PICALM transcript variant X5	XM_017018381.3:c.131-14936=	XM_017018381.3:c.131-14936G>A
PICALM transcript variant X13	XM_017018383.3:c.131-14936=	XM_017018383.3:c.131-14936G>A
PICALM transcript variant X14	XM_017018384.3:c.131-14936=	XM_017018384.3:c.131-14936G>A
PICALM transcript variant X16	XM_017018385.3:c.131-14936=	XM_017018385.3:c.131-14936G>A
PICALM transcript variant X18	XM_017018386.3:c.131-14936=	XM_017018386.3:c.131-14936G>A
PICALM transcript variant X19	XM_017018387.3:c.131-14936=	XM_017018387.3:c.131-14936G>A
PICALM transcript variant X20	XM_017018388.3:c.131-14936=	XM_017018388.3:c.131-14936G>A
PICALM transcript variant X4	XM_024448700.2:c.131-14936=	XM_024448700.2:c.131-14936G>A
PICALM transcript variant X7	XM_047427659.1:c.131-14936=	XM_047427659.1:c.131-14936G>A
PICALM transcript variant X8	XM_047427660.1:c.-23-14936=	XM_047427660.1:c.-23-14936G>A
PICALM transcript variant X10	XM_047427661.1:c.131-14936=	XM_047427661.1:c.131-14936G>A
PICALM transcript variant X11	XM_047427662.1:c.131-14936=	XM_047427662.1:c.131-14936G>A
PICALM transcript variant X17	XM_047427663.1:c.131-14936=	XM_047427663.1:c.131-14936G>A
PICALM transcript variant X21	XM_047427665.1:c.131-14936=	XM_047427665.1:c.131-14936G>A
PICALM transcript variant X23	XM_047427666.1:c.-23-14936=	XM_047427666.1:c.-23-14936G>A
PICALM transcript variant X24	XM_047427667.1:c.131-14936=	XM_047427667.1:c.131-14936G>A
PICALM transcript variant X25	XM_047427668.1:c.131-14936=	XM_047427668.1:c.131-14936G>A
PICALM transcript variant X26	XM_047427669.1:c.131-14936=	XM_047427669.1:c.131-14936G>A

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

111 SubSNP, 22 Frequency submissions

No	Submitter	Submission ID	Date (Build)
1	SC_JCM	ss851433	Aug 11, 2000 (83)
2	WI_SSAHASNP	ss12149027	Jul 11, 2003 (116)
3	PERLEGEN	ss14894340	Dec 05, 2003 (119)
4	SC_SNP	ss15634693	Feb 27, 2004 (120)
5	CSHL-HAPMAP	ss16558130	Feb 27, 2004 (120)
6	SSAHASNP	ss20852705	Apr 05, 2004 (121)
7	PERLEGEN	ss24211143	Sep 20, 2004 (123)
8	ABI	ss38802111	Mar 14, 2006 (126)
9	AFFY	ss65928986	Nov 30, 2006 (127)
10	AFFY	ss66369072	Nov 30, 2006 (127)
11	ILLUMINA	ss66592055	Nov 30, 2006 (127)
12	ILLUMINA	ss67498077	Nov 30, 2006 (127)
13	ILLUMINA	ss67858839	Nov 30, 2006 (127)
14	ILLUMINA	ss70886325	May 23, 2008 (130)
15	ILLUMINA	ss71478210	May 17, 2007 (127)
16	ILLUMINA	ss74901397	Dec 07, 2007 (129)
17	AFFY	ss76094270	Dec 07, 2007 (129)
18	HGSV	ss77546072	Dec 07, 2007 (129)
19	ILLUMINA	ss79233592	Dec 14, 2007 (130)
20	HGSV	ss80037282	Dec 14, 2007 (130)
21	HGSV	ss83499795	Dec 14, 2007 (130)
22	KRIBB_YJKIM	ss83515473	Dec 14, 2007 (130)
23	HGSV	ss83967008	Dec 14, 2007 (130)
24	BCMHGSC_JDW	ss88665965	Mar 24, 2008 (129)
25	HUMANGENOME_JCVI	ss97494930	Feb 04, 2009 (130)
26	BGI	ss106756557	Feb 04, 2009 (130)
27	1000GENOMES	ss110781710	Jan 25, 2009 (130)
28	1000GENOMES	ss114907344	Jan 25, 2009 (130)
29	ILLUMINA-UK	ss119924497	Dec 01, 2009 (131)
30	ILLUMINA	ss122616872	Dec 01, 2009 (131)
31	ENSEMBL	ss132696274	Dec 01, 2009 (131)
32	ILLUMINA	ss154382280	Dec 01, 2009 (131)
33	GMI	ss156562327	Dec 01, 2009 (131)
34	ILLUMINA	ss159558080	Dec 01, 2009 (131)
35	COMPLETE_GENOMICS	ss168647518	Jul 04, 2010 (132)
36	COMPLETE_GENOMICS	ss170491376	Jul 04, 2010 (132)
37	ILLUMINA	ss172191934	Jul 04, 2010 (132)
38	AFFY	ss172483539	Jul 04, 2010 (132)
39	ILLUMINA	ss174110198	Jul 04, 2010 (132)
40	COMPLETE_GENOMICS	ss175214239	Jul 04, 2010 (132)
41	BUSHMAN	ss202981190	Jul 04, 2010 (132)
42	BCM-HGSC-SUB	ss207596728	Jul 04, 2010 (132)
43	1000GENOMES	ss225361237	Jul 14, 2010 (132)
44	1000GENOMES	ss235644260	Jul 15, 2010 (132)
45	1000GENOMES	ss242258383	Jul 15, 2010 (132)
46	GMI	ss281095277	May 04, 2012 (137)
47	GMI	ss286421273	Apr 25, 2013 (138)
48	PJP	ss291088516	May 09, 2011 (134)
49	ILLUMINA	ss537391879	Sep 08, 2015 (146)
50	TISHKOFF	ss562707809	Apr 25, 2013 (138)
51	SSMP	ss658221050	Apr 25, 2013 (138)
52	ILLUMINA	ss825564110	Apr 01, 2015 (144)
53	ILLUMINA	ss833069240	Jul 13, 2019 (153)
54	EVA-GONL	ss988765868	Aug 21, 2014 (142)
55	JMKIDD_LAB	ss1077899651	Aug 21, 2014 (142)
56	1000GENOMES	ss1342231092	Aug 21, 2014 (142)
57	DDI	ss1426699854	Apr 01, 2015 (144)
58	EVA_GENOME_DK	ss1575839750	Apr 01, 2015 (144)
59	EVA_DECODE	ss1598430135	Apr 01, 2015 (144)
60	EVA_UK10K_ALSPAC	ss1627080372	Apr 01, 2015 (144)
61	EVA_UK10K_TWINSUK	ss1670074405	Apr 01, 2015 (144)
62	EVA_SVP	ss1713270693	Apr 01, 2015 (144)
63	HAMMER_LAB	ss1806913641	Sep 08, 2015 (146)
64	WEILL_CORNELL_DGM	ss1932124457	Feb 12, 2016 (147)
65	GENOMED	ss1967410048	Jul 19, 2016 (147)
66	JJLAB	ss2026804491	Sep 14, 2016 (149)
67	USC_VALOUEV	ss2155116559	Dec 20, 2016 (150)
68	HUMAN_LONGEVITY	ss2184246206	Dec 20, 2016 (150)
69	SYSTEMSBIOZJU	ss2627874616	Nov 08, 2017 (151)
70	GRF	ss2699413877	Nov 08, 2017 (151)
71	GNOMAD	ss2902381248	Nov 08, 2017 (151)
72	SWEGEN	ss3008480600	Nov 08, 2017 (151)
73	BIOINF_KMB_FNS_UNIBA	ss3027199822	Nov 08, 2017 (151)
74	CSHL	ss3349704394	Nov 08, 2017 (151)
75	ILLUMINA	ss3626708838	Oct 12, 2018 (152)
76	ILLUMINA	ss3637920345	Oct 12, 2018 (152)
77	ILLUMINA	ss3638973806	Oct 12, 2018 (152)
78	ILLUMINA	ss3639487973	Oct 12, 2018 (152)
79	ILLUMINA	ss3642917678	Oct 12, 2018 (152)
80	URBANLAB	ss3649659438	Oct 12, 2018 (152)
81	EGCUT_WGS	ss3675804040	Jul 13, 2019 (153)
82	EVA_DECODE	ss3692249142	Jul 13, 2019 (153)
83	ACPOP	ss3738377158	Jul 13, 2019 (153)
84	EVA	ss3749586352	Jul 13, 2019 (153)
85	PACBIO	ss3787013273	Jul 13, 2019 (153)
86	PACBIO	ss3792144473	Jul 13, 2019 (153)
87	PACBIO	ss3797026819	Jul 13, 2019 (153)
88	KHV_HUMAN_GENOMES	ss3814918524	Jul 13, 2019 (153)
89	EVA	ss3832743000	Apr 26, 2020 (154)
90	EVA	ss3839929555	Apr 26, 2020 (154)
91	EVA	ss3845410098	Apr 26, 2020 (154)
92	HGDP	ss3847425118	Apr 26, 2020 (154)
93	SGDP_PRJ	ss3876749299	Apr 26, 2020 (154)
94	KRGDB	ss3925173268	Apr 26, 2020 (154)
95	KOGIC	ss3970402021	Apr 26, 2020 (154)
96	EVA	ss3985546205	Apr 27, 2021 (155)
97	EVA	ss4017549560	Apr 27, 2021 (155)
98	TOPMED	ss4893573456	Apr 27, 2021 (155)
99	TOMMO_GENOMICS	ss5203070854	Apr 27, 2021 (155)
100	1000G_HIGH_COVERAGE	ss5288260435	Oct 16, 2022 (156)
101	HUGCELL_USP	ss5483332916	Oct 16, 2022 (156)
102	EVA	ss5510446028	Oct 16, 2022 (156)
103	1000G_HIGH_COVERAGE	ss5584403038	Oct 16, 2022 (156)
104	SANFORD_IMAGENETICS	ss5624280666	Oct 16, 2022 (156)
105	SANFORD_IMAGENETICS	ss5651697483	Oct 16, 2022 (156)
106	TOMMO_GENOMICS	ss5751289046	Oct 16, 2022 (156)
107	YY_MCH	ss5812616435	Oct 16, 2022 (156)
108	EVA	ss5836978394	Oct 16, 2022 (156)
109	EVA	ss5850068878	Oct 16, 2022 (156)
110	EVA	ss5920927912	Oct 16, 2022 (156)
111	EVA	ss5943019529	Oct 16, 2022 (156)
112	1000Genomes	NC_000011.9 - 85757589	Oct 12, 2018 (152)
113	1000Genomes_30x	NC_000011.10 - 86046547	Oct 16, 2022 (156)
114	The Avon Longitudinal Study of Parents and Children	NC_000011.9 - 85757589	Oct 12, 2018 (152)
115	Genetic variation in the Estonian population	NC_000011.9 - 85757589	Oct 12, 2018 (152)
116	The Danish reference pan genome	NC_000011.9 - 85757589	Apr 26, 2020 (154)
117	gnomAD - Genomes	NC_000011.10 - 86046547	Apr 27, 2021 (155)
118	Genome of the Netherlands Release 5	NC_000011.9 - 85757589	Apr 26, 2020 (154)
119	HGDP-CEPH-db Supplement 1	NC_000011.8 - 85435237	Apr 26, 2020 (154)
120	HapMap	NC_000011.10 - 86046547	Apr 26, 2020 (154)
121	KOREAN population from KRGDB	NC_000011.9 - 85757589	Apr 26, 2020 (154)
122	Korean Genome Project	NC_000011.10 - 86046547	Apr 26, 2020 (154)
123	Northern Sweden	NC_000011.9 - 85757589	Jul 13, 2019 (153)
124	Ancient Sardinia genome-wide 1240k capture data generation and analysis	NC_000011.9 - 85757589	Apr 27, 2021 (155)
125	Qatari	NC_000011.9 - 85757589	Apr 26, 2020 (154)
126	SGDP_PRJ	NC_000011.9 - 85757589	Apr 26, 2020 (154)
127	Siberian	NC_000011.9 - 85757589	Apr 26, 2020 (154)
128	8.3KJPN	NC_000011.9 - 85757589	Apr 27, 2021 (155)
129	14KJPN	NC_000011.10 - 86046547	Oct 16, 2022 (156)
130	TopMed	NC_000011.10 - 86046547	Apr 27, 2021 (155)
131	UK 10K study - Twins	NC_000011.9 - 85757589	Oct 12, 2018 (152)
132	A Vietnamese Genetic Variation Database	NC_000011.9 - 85757589	Jul 13, 2019 (153)
133	ALFA	NC_000011.10 - 86046547	Apr 27, 2021 (155)

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID	History Updated (Build)
rs17817328	Oct 08, 2004 (123)
rs57185288	May 23, 2008 (130)

Added to this RefSNP Cluster:

Submission IDs	Observation SPDI	Canonical SPDI	Source RSIDs
103010, ss66369072, ss76094270, ss77546072, ss80037282, ss83499795, ss83967008, ss88665965, ss110781710, ss114907344, ss119924497, ss168647518, ss170491376, ss172483539, ss175214239, ss202981190, ss207596728, ss281095277, ss286421273, ss291088516, ss825564110, ss1598430135, ss1713270693, ss3638973806, ss3639487973, ss3642917678, ss3847425118	NC_000011.8:85435236:C:T	NC_000011.10:86046546:C:T	(self)
54785918, 30411935, 21542288, 2656408, 13567424, 32350662, 11662023, 772132, 14166387, 28766279, 7632913, 61040161, 30411935, 6744018, ss225361237, ss235644260, ss242258383, ss537391879, ss562707809, ss658221050, ss833069240, ss988765868, ss1077899651, ss1342231092, ss1426699854, ss1575839750, ss1627080372, ss1670074405, ss1806913641, ss1932124457, ss1967410048, ss2026804491, ss2155116559, ss2627874616, ss2699413877, ss2902381248, ss3008480600, ss3349704394, ss3626708838, ss3637920345, ss3675804040, ss3738377158, ss3749586352, ss3787013273, ss3792144473, ss3797026819, ss3832743000, ss3839929555, ss3876749299, ss3925173268, ss3985546205, ss4017549560, ss5203070854, ss5510446028, ss5624280666, ss5651697483, ss5836978394, ss5943019529	NC_000011.9:85757588:C:T	NC_000011.10:86046546:C:T	(self)
71928973, 386673691, 655833, 26780022, 85126150, 109119112, 5331082426, ss2184246206, ss3027199822, ss3649659438, ss3692249142, ss3814918524, ss3845410098, ss3970402021, ss4893573456, ss5288260435, ss5483332916, ss5584403038, ss5751289046, ss5812616435, ss5850068878, ss5920927912	NC_000011.10:86046546:C:T	NC_000011.10:86046546:C:T	(self)
ss12149027	NT_033927.5:15956616:C:T	NC_000011.10:86046546:C:T	(self)
ss15634693, ss16558130, ss20852705	NT_033927.6:15956617:C:T	NC_000011.10:86046546:C:T	(self)
ss851433, ss14894340, ss24211143, ss38802111, ss65928986, ss66592055, ss67498077, ss67858839, ss70886325, ss71478210, ss74901397, ss79233592, ss83515473, ss97494930, ss106756557, ss122616872, ss132696274, ss154382280, ss156562327, ss159558080, ss172191934, ss174110198	NT_167190.1:31063383:C:T	NC_000011.10:86046546:C:T	(self)

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

2 citations for rs677909

PMID	Title	Author	Year	Journal
20697030	Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.	Jun G et al.	2010	Archives of neurology
28870582	Linking Alzheimer's disease and type 2 diabetes: Novel shared susceptibility genes detected by cFDR approach.	Wang XF et al.	2017	Journal of the neurological sciences

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:

Select flank length:

Genomic regions, transcripts, and products
Top▲ Help
NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

Choose placement

dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

Reference SNP (rs) Report

rs677909