Name: rs4552569
Published: September 21, 2022
License: Open Access

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs4552569

Current Build 156

Released September 21, 2022

Organism: Homo sapiens
Position: chr5:83877774 (GRCh38.p14) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
Alleles: C>A / C>G / C>T
Variation Type: SNV Single Nucleotide Variation
Frequency: C=0.255181 (85621/335530, ALFA)
C=0.252907 (66942/264690, TOPMED)
C=0.246911 (34576/140034, GnomAD) (+ 21 more)
C=0.25403 (19981/78656, PAGE_STUDY)
C=0.25975 (7340/28258, 14KJPN)
C=0.26092 (4373/16760, 8.3KJPN)
C=0.2402 (1538/6404, 1000G_30x)
C=0.2384 (1194/5008, 1000G)
C=0.1944 (871/4480, Estonian)
C=0.2372 (914/3854, ALSPAC)
C=0.2395 (888/3708, TWINSUK)
C=0.2819 (826/2930, KOREAN)
C=0.2831 (590/2084, HGDP_Stanford)
C=0.2519 (476/1890, HapMap)
C=0.2915 (534/1832, Korea1K)
C=0.223 (223/998, GoNL)
C=0.339 (268/790, PRJEB37584)
C=0.185 (111/600, NorthernSweden)
C=0.212 (111/524, SGDP_PRJ)
C=0.310 (67/216, Qatari)
C=0.212 (45/212, Vietnamese)
C=0.14 (8/56, Siberian)
C=0.27 (12/44, Ancient Sardinia)
C=0.20 (8/40, GENOME_DK)

Clinical Significance: Not Reported in ClinVar
Gene : Consequence: None
Publications: 2 citations
Genomic View: See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20230706150541

Population	Group	Sample Size	Ref Allele	Alt Allele
Total	Global	340660	C=0.255078	T=0.744922
European	Sub	297168	C=0.254206	T=0.745794
African	Sub	9776	C=0.2256	T=0.7744
African Others	Sub	384	C=0.208	T=0.792
African American	Sub	9392	C=0.2263	T=0.7737
Asian	Sub	3980	C=0.2751	T=0.7249
East Asian	Sub	3204	C=0.2981	T=0.7019
Other Asian	Sub	776	C=0.180	T=0.820
Latin American 1	Sub	1280	C=0.2477	T=0.7523
Latin American 2	Sub	9336	C=0.3255	T=0.6745
South Asian	Sub	5234	C=0.2054	T=0.7946
Other	Sub	13886	C=0.26084	T=0.73916

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

Download

Study	Population	Group	Sample Size	Ref Allele	Alt Allele
Allele Frequency Aggregator	Total	Global	335530	C=0.255181	T=0.744819
Allele Frequency Aggregator	European	Sub	293998	C=0.254253	T=0.745747
Allele Frequency Aggregator	Other	Sub	13068	C=0.26209	T=0.73791
Allele Frequency Aggregator	Latin American 2	Sub	9336	C=0.3255	T=0.6745
Allele Frequency Aggregator	African	Sub	8634	C=0.2224	T=0.7776
Allele Frequency Aggregator	South Asian	Sub	5234	C=0.2054	T=0.7946
Allele Frequency Aggregator	Asian	Sub	3980	C=0.2751	T=0.7249
Allele Frequency Aggregator	Latin American 1	Sub	1280	C=0.2477	T=0.7523
TopMed	Global	Study-wide	264690	C=0.252907	T=0.747093
gnomAD - Genomes	Global	Study-wide	140034	C=0.246911	T=0.753089
gnomAD - Genomes	European	Sub	75864	C=0.25423	T=0.74577
gnomAD - Genomes	African	Sub	41946	C=0.21630	T=0.78370
gnomAD - Genomes	American	Sub	13634	C=0.29162	T=0.70838
gnomAD - Genomes	Ashkenazi Jewish	Sub	3322	C=0.2315	T=0.7685
gnomAD - Genomes	East Asian	Sub	3116	C=0.2863	T=0.7137
gnomAD - Genomes	Other	Sub	2152	C=0.2691	T=0.7309
The PAGE Study	Global	Study-wide	78656	C=0.25403	T=0.74597
The PAGE Study	AfricanAmerican	Sub	32504	C=0.22056	T=0.77944
The PAGE Study	Mexican	Sub	10800	C=0.33713	T=0.66287
The PAGE Study	Asian	Sub	8312	C=0.2519	T=0.7481
The PAGE Study	PuertoRican	Sub	7916	C=0.2303	T=0.7697
The PAGE Study	NativeHawaiian	Sub	4528	C=0.2438	T=0.7562
The PAGE Study	Cuban	Sub	4230	C=0.2865	T=0.7135
The PAGE Study	Dominican	Sub	3828	C=0.2675	T=0.7325
The PAGE Study	CentralAmerican	Sub	2446	C=0.3193	T=0.6807
The PAGE Study	SouthAmerican	Sub	1982	C=0.3133	T=0.6867
The PAGE Study	NativeAmerican	Sub	1254	C=0.2799	T=0.7201
The PAGE Study	SouthAsian	Sub	856	C=0.188	T=0.812
14KJPN	JAPANESE	Study-wide	28258	C=0.25975	T=0.74025
8.3KJPN	JAPANESE	Study-wide	16760	C=0.26092	T=0.73908
1000Genomes_30x	Global	Study-wide	6404	C=0.2402	T=0.7598
1000Genomes_30x	African	Sub	1786	C=0.2178	T=0.7822
1000Genomes_30x	Europe	Sub	1266	C=0.2662	T=0.7338
1000Genomes_30x	South Asian	Sub	1202	C=0.1997	T=0.8003
1000Genomes_30x	East Asian	Sub	1170	C=0.2607	T=0.7393
1000Genomes_30x	American	Sub	980	C=0.272	T=0.728
1000Genomes	Global	Study-wide	5008	C=0.2384	T=0.7616
1000Genomes	African	Sub	1322	C=0.2194	T=0.7806
1000Genomes	East Asian	Sub	1008	C=0.2550	T=0.7450
1000Genomes	Europe	Sub	1006	C=0.2674	T=0.7326
1000Genomes	South Asian	Sub	978	C=0.191	T=0.809
1000Genomes	American	Sub	694	C=0.275	T=0.725
Genetic variation in the Estonian population	Estonian	Study-wide	4480	C=0.1944	T=0.8056
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.2372	T=0.7628
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.2395	T=0.7605
KOREAN population from KRGDB	KOREAN	Study-wide	2930	C=0.2819	A=0.0000, G=0.0000, T=0.7181
HGDP-CEPH-db Supplement 1	Global	Study-wide	2084	C=0.2831	T=0.7169
HGDP-CEPH-db Supplement 1	Est_Asia	Sub	470	C=0.283	T=0.717
HGDP-CEPH-db Supplement 1	Central_South_Asia	Sub	414	C=0.287	T=0.713
HGDP-CEPH-db Supplement 1	Middle_Est	Sub	350	C=0.297	T=0.703
HGDP-CEPH-db Supplement 1	Europe	Sub	320	C=0.228	T=0.772
HGDP-CEPH-db Supplement 1	Africa	Sub	242	C=0.190	T=0.810
HGDP-CEPH-db Supplement 1	America	Sub	216	C=0.366	T=0.634
HGDP-CEPH-db Supplement 1	Oceania	Sub	72	C=0.50	T=0.50
HapMap	Global	Study-wide	1890	C=0.2519	T=0.7481
HapMap	American	Sub	770	C=0.242	T=0.758
HapMap	African	Sub	690	C=0.238	T=0.762
HapMap	Asian	Sub	254	C=0.307	T=0.693
HapMap	Europe	Sub	176	C=0.273	T=0.727
Korean Genome Project	KOREAN	Study-wide	1832	C=0.2915	T=0.7085
Genome of the Netherlands Release 5	Genome of the Netherlands	Study-wide	998	C=0.223	T=0.777
CNV burdens in cranial meningiomas	Global	Study-wide	790	C=0.339	T=0.661
CNV burdens in cranial meningiomas	CRM	Sub	790	C=0.339	T=0.661
Northern Sweden	ACPOP	Study-wide	600	C=0.185	T=0.815
SGDP_PRJ	Global	Study-wide	524	C=0.212	T=0.788
Qatari	Global	Study-wide	216	C=0.310	T=0.690
A Vietnamese Genetic Variation Database	Global	Study-wide	212	C=0.212	T=0.788
Siberian	Global	Study-wide	56	C=0.14	T=0.86
Ancient Sardinia genome-wide 1240k capture data generation and analysis	Global	Study-wide	44	C=0.27	T=0.73
The Danish reference pan genome	Danish	Study-wide	40	C=0.20	T=0.80

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements

Sequence name	Change
GRCh38.p14 chr 5	NC_000005.10:g.83877774C>A
GRCh38.p14 chr 5	NC_000005.10:g.83877774C>G
GRCh38.p14 chr 5	NC_000005.10:g.83877774C>T
GRCh37.p13 chr 5	NC_000005.9:g.83173593C>A
GRCh37.p13 chr 5	NC_000005.9:g.83173593C>G
GRCh37.p13 chr 5	NC_000005.9:g.83173593C>T

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement	C=	A	G	T
GRCh38.p14 chr 5	NC_000005.10:g.83877774=	NC_000005.10:g.83877774C>A	NC_000005.10:g.83877774C>G	NC_000005.10:g.83877774C>T
GRCh37.p13 chr 5	NC_000005.9:g.83173593=	NC_000005.9:g.83173593C>A	NC_000005.9:g.83173593C>G	NC_000005.9:g.83173593C>T

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

152 SubSNP, 24 Frequency submissions

No	Submitter	Submission ID	Date (Build)
1	SC_JCM	ss6150643	Feb 20, 2003 (111)
2	WI_SSAHASNP	ss14660842	Dec 05, 2003 (119)
3	SSAHASNP	ss22309130	Apr 05, 2004 (121)
4	PERLEGEN	ss24135976	Sep 20, 2004 (123)
5	ABI	ss44671782	Mar 13, 2006 (126)
6	ILLUMINA	ss66560777	Nov 30, 2006 (127)
7	ILLUMINA	ss67345375	Nov 30, 2006 (127)
8	ILLUMINA	ss67739012	Nov 30, 2006 (127)
9	ILLUMINA	ss70809204	May 27, 2008 (130)
10	ILLUMINA	ss71389179	May 17, 2007 (127)
11	ILLUMINA	ss75794331	Dec 06, 2007 (129)
12	AFFY	ss76466202	Dec 06, 2007 (129)
13	ILLUMINA	ss79185296	Dec 16, 2007 (130)
14	HGSV	ss80640391	Dec 16, 2007 (130)
15	KRIBB_YJKIM	ss84289391	Dec 16, 2007 (130)
16	BCMHGSC_JDW	ss93156442	Mar 24, 2008 (129)
17	HUMANGENOME_JCVI	ss98629083	Feb 06, 2009 (130)
18	BGI	ss104211806	Dec 01, 2009 (131)
19	1000GENOMES	ss109177429	Jan 23, 2009 (130)
20	1000GENOMES	ss112111684	Jan 25, 2009 (130)
21	ILLUMINA-UK	ss116693241	Feb 14, 2009 (130)
22	ILLUMINA	ss122329160	Dec 01, 2009 (131)
23	ENSEMBL	ss142888057	Dec 01, 2009 (131)
24	ENSEMBL	ss143251140	Dec 01, 2009 (131)
25	ILLUMINA	ss154299926	Dec 01, 2009 (131)
26	GMI	ss155671594	Dec 01, 2009 (131)
27	ILLUMINA	ss159476770	Dec 01, 2009 (131)
28	ILLUMINA	ss160687031	Dec 01, 2009 (131)
29	COMPLETE_GENOMICS	ss162412586	Jul 04, 2010 (132)
30	COMPLETE_GENOMICS	ss165380452	Jul 04, 2010 (132)
31	COMPLETE_GENOMICS	ss166758034	Jul 04, 2010 (132)
32	ILLUMINA	ss171821713	Jul 04, 2010 (132)
33	ILLUMINA	ss173751700	Jul 04, 2010 (132)
34	BUSHMAN	ss200473384	Jul 04, 2010 (132)
35	BCM-HGSC-SUB	ss206715731	Jul 04, 2010 (132)
36	1000GENOMES	ss221779242	Jul 14, 2010 (132)
37	1000GENOMES	ss233017731	Jul 14, 2010 (132)
38	1000GENOMES	ss240174540	Jul 15, 2010 (132)
39	BL	ss253586435	May 09, 2011 (134)
40	GMI	ss278361934	May 04, 2012 (137)
41	GMI	ss285208902	Apr 25, 2013 (138)
42	PJP	ss293392874	May 09, 2011 (134)
43	ILLUMINA	ss480968486	May 04, 2012 (137)
44	ILLUMINA	ss480988575	May 04, 2012 (137)
45	ILLUMINA	ss481962234	Sep 08, 2015 (146)
46	ILLUMINA	ss485279170	May 04, 2012 (137)
47	ILLUMINA	ss537245130	Sep 08, 2015 (146)
48	TISHKOFF	ss558511008	Apr 25, 2013 (138)
49	SSMP	ss652385011	Apr 25, 2013 (138)
50	ILLUMINA	ss778538680	Sep 08, 2015 (146)
51	ILLUMINA	ss783085506	Sep 08, 2015 (146)
52	ILLUMINA	ss784043044	Sep 08, 2015 (146)
53	ILLUMINA	ss825515814	Apr 01, 2015 (144)
54	ILLUMINA	ss832343902	Sep 08, 2015 (146)
55	ILLUMINA	ss832988223	Jul 13, 2019 (153)
56	ILLUMINA	ss833995283	Sep 08, 2015 (146)
57	EVA-GONL	ss981762689	Aug 21, 2014 (142)
58	JMKIDD_LAB	ss1072775515	Aug 21, 2014 (142)
59	1000GENOMES	ss1315841220	Aug 21, 2014 (142)
60	DDI	ss1430402368	Apr 01, 2015 (144)
61	EVA_GENOME_DK	ss1581213418	Apr 01, 2015 (144)
62	EVA_DECODE	ss1591280836	Apr 01, 2015 (144)
63	EVA_UK10K_ALSPAC	ss1613282403	Apr 01, 2015 (144)
64	EVA_UK10K_TWINSUK	ss1656276436	Apr 01, 2015 (144)
65	EVA_SVP	ss1712778105	Apr 01, 2015 (144)
66	ILLUMINA	ss1752587723	Sep 08, 2015 (146)
67	HAMMER_LAB	ss1803772982	Sep 08, 2015 (146)
68	WEILL_CORNELL_DGM	ss1925017338	Feb 12, 2016 (147)
69	ILLUMINA	ss1946148711	Feb 12, 2016 (147)
70	ILLUMINA	ss1958800748	Feb 12, 2016 (147)
71	GENOMED	ss1970132366	Jul 19, 2016 (147)
72	JJLAB	ss2023115244	Sep 14, 2016 (149)
73	ILLUMINA	ss2094818726	Dec 20, 2016 (150)
74	ILLUMINA	ss2095157944	Dec 20, 2016 (150)
75	USC_VALOUEV	ss2151271687	Dec 20, 2016 (150)
76	HUMAN_LONGEVITY	ss2275245644	Dec 20, 2016 (150)
77	SYSTEMSBIOZJU	ss2626054744	Nov 08, 2017 (151)
78	ILLUMINA	ss2634302328	Nov 08, 2017 (151)
79	GRF	ss2706824261	Nov 08, 2017 (151)
80	ILLUMINA	ss2711042603	Nov 08, 2017 (151)
81	GNOMAD	ss2826793096	Nov 08, 2017 (151)
82	AFFY	ss2985325962	Nov 08, 2017 (151)
83	AFFY	ss2985958032	Nov 08, 2017 (151)
84	SWEGEN	ss2997242972	Nov 08, 2017 (151)
85	ILLUMINA	ss3022503978	Nov 08, 2017 (151)
86	BIOINF_KMB_FNS_UNIBA	ss3025342825	Nov 08, 2017 (151)
87	CSHL	ss3346473187	Nov 08, 2017 (151)
88	ILLUMINA	ss3625876924	Oct 12, 2018 (152)
89	ILLUMINA	ss3629274991	Oct 12, 2018 (152)
90	ILLUMINA	ss3632228185	Oct 12, 2018 (152)
91	ILLUMINA	ss3633380396	Oct 12, 2018 (152)
92	ILLUMINA	ss3634101216	Oct 12, 2018 (152)
93	ILLUMINA	ss3635010035	Oct 12, 2018 (152)
94	ILLUMINA	ss3635783133	Oct 12, 2018 (152)
95	ILLUMINA	ss3636722011	Oct 12, 2018 (152)
96	ILLUMINA	ss3637535763	Oct 12, 2018 (152)
97	ILLUMINA	ss3638564062	Oct 12, 2018 (152)
98	ILLUMINA	ss3639284688	Oct 12, 2018 (152)
99	ILLUMINA	ss3639665938	Oct 12, 2018 (152)
100	ILLUMINA	ss3640717328	Oct 12, 2018 (152)
101	ILLUMINA	ss3641181756	Oct 12, 2018 (152)
102	ILLUMINA	ss3641478685	Oct 12, 2018 (152)
103	ILLUMINA	ss3643509309	Oct 12, 2018 (152)
104	ILLUMINA	ss3644881673	Oct 12, 2018 (152)
105	URBANLAB	ss3648103890	Oct 12, 2018 (152)
106	ILLUMINA	ss3653000970	Oct 12, 2018 (152)
107	ILLUMINA	ss3654099838	Oct 12, 2018 (152)
108	EGCUT_WGS	ss3665123272	Jul 13, 2019 (153)
109	EVA_DECODE	ss3715046138	Jul 13, 2019 (153)
110	ILLUMINA	ss3726246881	Jul 13, 2019 (153)
111	ACPOP	ss3732518975	Jul 13, 2019 (153)
112	ILLUMINA	ss3744255553	Jul 13, 2019 (153)
113	ILLUMINA	ss3744537366	Jul 13, 2019 (153)
114	ILLUMINA	ss3745310237	Jul 13, 2019 (153)
115	EVA	ss3763654919	Jul 13, 2019 (153)
116	PAGE_CC	ss3771213509	Jul 13, 2019 (153)
117	ILLUMINA	ss3772804361	Jul 13, 2019 (153)
118	PACBIO	ss3785162305	Jul 13, 2019 (153)
119	PACBIO	ss3790560422	Jul 13, 2019 (153)
120	PACBIO	ss3795437022	Jul 13, 2019 (153)
121	KHV_HUMAN_GENOMES	ss3806821965	Jul 13, 2019 (153)
122	EVA	ss3829337599	Apr 26, 2020 (154)
123	EVA	ss3838142464	Apr 26, 2020 (154)
124	EVA	ss3843583656	Apr 26, 2020 (154)
125	HGDP	ss3847796841	Apr 26, 2020 (154)
126	SGDP_PRJ	ss3862256941	Apr 26, 2020 (154)
127	KRGDB	ss3908838962	Apr 26, 2020 (154)
128	KOGIC	ss3957035891	Apr 26, 2020 (154)
129	EVA	ss3984549902	Apr 26, 2021 (155)
130	EVA	ss3985152318	Apr 26, 2021 (155)
131	EVA	ss4017216284	Apr 26, 2021 (155)
132	TOPMED	ss4666488587	Apr 26, 2021 (155)
133	TOMMO_GENOMICS	ss5172611702	Apr 26, 2021 (155)
134	1000G_HIGH_COVERAGE	ss5264637713	Oct 13, 2022 (156)
135	EVA	ss5315065154	Oct 13, 2022 (156)
136	EVA	ss5358768163	Oct 13, 2022 (156)
137	HUGCELL_USP	ss5462742467	Oct 13, 2022 (156)
138	EVA	ss5508087054	Oct 13, 2022 (156)
139	1000G_HIGH_COVERAGE	ss5548626020	Oct 13, 2022 (156)
140	SANFORD_IMAGENETICS	ss5624593851	Oct 13, 2022 (156)
141	SANFORD_IMAGENETICS	ss5638183998	Oct 13, 2022 (156)
142	TOMMO_GENOMICS	ss5709254945	Oct 13, 2022 (156)
143	EVA	ss5799653989	Oct 13, 2022 (156)
144	YY_MCH	ss5806482952	Oct 13, 2022 (156)
145	EVA	ss5835182704	Oct 13, 2022 (156)
146	EVA	ss5847269395	Oct 13, 2022 (156)
147	EVA	ss5848055371	Oct 13, 2022 (156)
148	EVA	ss5854890076	Oct 13, 2022 (156)
149	EVA	ss5894934725	Oct 13, 2022 (156)
150	EVA	ss5966619760	Oct 13, 2022 (156)
151	EVA	ss5979745261	Oct 13, 2022 (156)
152	EVA	ss5980303670	Oct 13, 2022 (156)
153	1000Genomes	NC_000005.9 - 83173593	Oct 12, 2018 (152)
154	1000Genomes_30x	NC_000005.10 - 83877774	Oct 13, 2022 (156)
155	The Avon Longitudinal Study of Parents and Children	NC_000005.9 - 83173593	Oct 12, 2018 (152)
156	Genetic variation in the Estonian population	NC_000005.9 - 83173593	Oct 12, 2018 (152)
157	The Danish reference pan genome	NC_000005.9 - 83173593	Apr 26, 2020 (154)
158	gnomAD - Genomes	NC_000005.10 - 83877774	Apr 26, 2021 (155)
159	Genome of the Netherlands Release 5	NC_000005.9 - 83173593	Apr 26, 2020 (154)
160	HGDP-CEPH-db Supplement 1	NC_000005.8 - 83209349	Apr 26, 2020 (154)
161	HapMap	NC_000005.10 - 83877774	Apr 26, 2020 (154)
162	KOREAN population from KRGDB	NC_000005.9 - 83173593	Apr 26, 2020 (154)
163	Korean Genome Project	NC_000005.10 - 83877774	Apr 26, 2020 (154)
164	Northern Sweden	NC_000005.9 - 83173593	Jul 13, 2019 (153)
165	The PAGE Study	NC_000005.10 - 83877774	Jul 13, 2019 (153)
166	Ancient Sardinia genome-wide 1240k capture data generation and analysis	NC_000005.9 - 83173593	Apr 26, 2021 (155)
167	CNV burdens in cranial meningiomas	NC_000005.9 - 83173593	Apr 26, 2021 (155)
168	Qatari	NC_000005.9 - 83173593	Apr 26, 2020 (154)
169	SGDP_PRJ	NC_000005.9 - 83173593	Apr 26, 2020 (154)
170	Siberian	NC_000005.9 - 83173593	Apr 26, 2020 (154)
171	8.3KJPN	NC_000005.9 - 83173593	Apr 26, 2021 (155)
172	14KJPN	NC_000005.10 - 83877774	Oct 13, 2022 (156)
173	TopMed	NC_000005.10 - 83877774	Apr 26, 2021 (155)
174	UK 10K study - Twins	NC_000005.9 - 83173593	Oct 12, 2018 (152)
175	A Vietnamese Genetic Variation Database	NC_000005.9 - 83173593	Jul 13, 2019 (153)
176	ALFA	NC_000005.10 - 83877774	Apr 26, 2021 (155)

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID	History Updated (Build)
rs61566952	May 27, 2008 (130)

Added to this RefSNP Cluster:

Submission IDs	Observation SPDI	Canonical SPDI	Source RSIDs
16016356, ss3908838962	NC_000005.9:83173592:C:A	NC_000005.10:83877773:C:A	(self)
16016356, ss3908838962	NC_000005.9:83173592:C:G	NC_000005.10:83877773:C:G	(self)
474733, ss80640391, ss93156442, ss109177429, ss112111684, ss116693241, ss162412586, ss165380452, ss166758034, ss200473384, ss206715731, ss253586435, ss278361934, ss285208902, ss293392874, ss480968486, ss825515814, ss1591280836, ss1712778105, ss3639284688, ss3639665938, ss3643509309, ss3847796841	NC_000005.8:83209348:C:T	NC_000005.10:83877773:C:T	(self)
27469257, 15274041, 10861520, 7378357, 6790429, 16016356, 5803840, 378245, 99271, 7059268, 14273921, 3788041, 30581009, 15274041, 3390257, ss221779242, ss233017731, ss240174540, ss480988575, ss481962234, ss485279170, ss537245130, ss558511008, ss652385011, ss778538680, ss783085506, ss784043044, ss832343902, ss832988223, ss833995283, ss981762689, ss1072775515, ss1315841220, ss1430402368, ss1581213418, ss1613282403, ss1656276436, ss1752587723, ss1803772982, ss1925017338, ss1946148711, ss1958800748, ss1970132366, ss2023115244, ss2094818726, ss2095157944, ss2151271687, ss2626054744, ss2634302328, ss2706824261, ss2711042603, ss2826793096, ss2985325962, ss2985958032, ss2997242972, ss3022503978, ss3346473187, ss3625876924, ss3629274991, ss3632228185, ss3633380396, ss3634101216, ss3635010035, ss3635783133, ss3636722011, ss3637535763, ss3638564062, ss3640717328, ss3641181756, ss3641478685, ss3644881673, ss3653000970, ss3654099838, ss3665123272, ss3732518975, ss3744255553, ss3744537366, ss3745310237, ss3763654919, ss3772804361, ss3785162305, ss3790560422, ss3795437022, ss3829337599, ss3838142464, ss3862256941, ss3908838962, ss3984549902, ss3985152318, ss4017216284, ss5172611702, ss5315065154, ss5358768163, ss5508087054, ss5624593851, ss5638183998, ss5799653989, ss5835182704, ss5847269395, ss5848055371, ss5966619760, ss5979745261, ss5980303670	NC_000005.9:83173592:C:T	NC_000005.10:83877773:C:T	(self)
36151955, 194184660, 2903373, 13413892, 434978, 43092049, 503866144, 254214872, ss2275245644, ss3025342825, ss3648103890, ss3715046138, ss3726246881, ss3771213509, ss3806821965, ss3843583656, ss3957035891, ss4666488587, ss5264637713, ss5462742467, ss5548626020, ss5709254945, ss5806482952, ss5854890076, ss5894934725	NC_000005.10:83877773:C:T	NC_000005.10:83877773:C:T	(self)
ss14660842, ss22309130	NT_006713.13:12565724:C:T	NC_000005.10:83877773:C:T	(self)
ss6150643, ss24135976, ss44671782, ss66560777, ss67345375, ss67739012, ss70809204, ss71389179, ss75794331, ss76466202, ss79185296, ss84289391, ss98629083, ss104211806, ss122329160, ss142888057, ss143251140, ss154299926, ss155671594, ss159476770, ss160687031, ss171821713, ss173751700	NT_006713.15:33767951:C:T	NC_000005.10:83877773:C:T	(self)

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

2 citations for rs4552569

PMID	Title	Author	Year	Journal
22138694	A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis.	Lin Z et al.	2011	Nature genetics
27047576	Association Study of Single Nucleotide Polymorphisms Rs4552569/Rs17095830 with Ankylosing Spondylitis in A Chinese Population.	Wang Q et al.	2016	The open rheumatology journal

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:

Select flank length:

Genomic regions, transcripts, and products
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NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

Reference SNP (rs) Report

rs4552569