Name: rs2634073
Published: September 21, 2022
License: Open Access

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs2634073

Current Build 156

Released September 21, 2022

Organism: Homo sapiens
Position: chr4:110744627 (GRCh38.p14) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
Alleles: T>C
Variation Type: SNV Single Nucleotide Variation
Frequency: T=0.327542 (86697/264690, TOPMED)
T=0.218024 (41230/189108, ALFA)
T=0.300774 (42023/139716, GnomAD) (+ 20 more)
T=0.43497 (34233/78702, PAGE_STUDY)
C=0.31899 (9014/28258, 14KJPN)
C=0.31999 (5363/16760, 8.3KJPN)
T=0.4299 (2753/6404, 1000G_30x)
T=0.4351 (2179/5008, 1000G)
T=0.1911 (856/4480, Estonian)
T=0.1622 (625/3854, ALSPAC)
T=0.1607 (596/3708, TWINSUK)
C=0.2966 (869/2930, KOREAN)
T=0.4573 (953/2084, HGDP_Stanford)
T=0.4259 (805/1890, HapMap)
T=0.144 (144/998, GoNL)
C=0.280 (220/786, PRJEB37584)
T=0.147 (88/600, NorthernSweden)
T=0.291 (125/430, SGDP_PRJ)
T=0.375 (81/216, Qatari)
C=0.194 (42/216, Vietnamese)
T=0.30 (16/54, Ancient Sardinia)
T=0.21 (9/42, Siberian)
T=0.25 (10/40, GENOME_DK)

Clinical Significance: Not Reported in ClinVar
Gene : Consequence: None
Publications: 4 citations
Genomic View: See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20230706150541

Population	Group	Sample Size	Ref Allele	Alt Allele
Total	Global	189108	T=0.218024	C=0.781976
European	Sub	165808	T=0.196450	C=0.803550
African	Sub	7490	T=0.4244	C=0.5756
African Others	Sub	262	T=0.412	C=0.588
African American	Sub	7228	T=0.4249	C=0.5751
Asian	Sub	732	T=0.731	C=0.269
East Asian	Sub	588	T=0.728	C=0.272
Other Asian	Sub	144	T=0.743	C=0.257
Latin American 1	Sub	776	T=0.314	C=0.686
Latin American 2	Sub	2834	T=0.4065	C=0.5935
South Asian	Sub	5048	T=0.3427	C=0.6573
Other	Sub	6420	T=0.2830	C=0.7170

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

Download

Study	Population	Group	Sample Size	Ref Allele	Alt Allele
TopMed	Global	Study-wide	264690	T=0.327542	C=0.672458
Allele Frequency Aggregator	Total	Global	189108	T=0.218024	C=0.781976
Allele Frequency Aggregator	European	Sub	165808	T=0.196450	C=0.803550
Allele Frequency Aggregator	African	Sub	7490	T=0.4244	C=0.5756
Allele Frequency Aggregator	Other	Sub	6420	T=0.2830	C=0.7170
Allele Frequency Aggregator	South Asian	Sub	5048	T=0.3427	C=0.6573
Allele Frequency Aggregator	Latin American 2	Sub	2834	T=0.4065	C=0.5935
Allele Frequency Aggregator	Latin American 1	Sub	776	T=0.314	C=0.686
Allele Frequency Aggregator	Asian	Sub	732	T=0.731	C=0.269
gnomAD - Genomes	Global	Study-wide	139716	T=0.300774	C=0.699226
gnomAD - Genomes	European	Sub	75752	T=0.19507	C=0.80493
gnomAD - Genomes	African	Sub	41872	T=0.41687	C=0.58313
gnomAD - Genomes	American	Sub	13542	T=0.40814	C=0.59186
gnomAD - Genomes	Ashkenazi Jewish	Sub	3314	T=0.3890	C=0.6110
gnomAD - Genomes	East Asian	Sub	3096	T=0.7494	C=0.2506
gnomAD - Genomes	Other	Sub	2140	T=0.3061	C=0.6939
The PAGE Study	Global	Study-wide	78702	T=0.43497	C=0.56503
The PAGE Study	AfricanAmerican	Sub	32516	T=0.41487	C=0.58513
The PAGE Study	Mexican	Sub	10810	T=0.43451	C=0.56549
The PAGE Study	Asian	Sub	8318	T=0.6881	C=0.3119
The PAGE Study	PuertoRican	Sub	7918	T=0.3449	C=0.6551
The PAGE Study	NativeHawaiian	Sub	4534	T=0.4824	C=0.5176
The PAGE Study	Cuban	Sub	4230	T=0.2908	C=0.7092
The PAGE Study	Dominican	Sub	3828	T=0.3493	C=0.6507
The PAGE Study	CentralAmerican	Sub	2450	T=0.4894	C=0.5106
The PAGE Study	SouthAmerican	Sub	1982	T=0.4738	C=0.5262
The PAGE Study	NativeAmerican	Sub	1260	T=0.2841	C=0.7159
The PAGE Study	SouthAsian	Sub	856	T=0.398	C=0.602
14KJPN	JAPANESE	Study-wide	28258	T=0.68101	C=0.31899
8.3KJPN	JAPANESE	Study-wide	16760	T=0.68001	C=0.31999
1000Genomes_30x	Global	Study-wide	6404	T=0.4299	C=0.5701
1000Genomes_30x	African	Sub	1786	T=0.4345	C=0.5655
1000Genomes_30x	Europe	Sub	1266	T=0.2164	C=0.7836
1000Genomes_30x	South Asian	Sub	1202	T=0.3661	C=0.6339
1000Genomes_30x	East Asian	Sub	1170	T=0.7282	C=0.2718
1000Genomes_30x	American	Sub	980	T=0.419	C=0.581
1000Genomes	Global	Study-wide	5008	T=0.4351	C=0.5649
1000Genomes	African	Sub	1322	T=0.4402	C=0.5598
1000Genomes	East Asian	Sub	1008	T=0.7192	C=0.2808
1000Genomes	Europe	Sub	1006	T=0.2187	C=0.7813
1000Genomes	South Asian	Sub	978	T=0.364	C=0.636
1000Genomes	American	Sub	694	T=0.427	C=0.573
Genetic variation in the Estonian population	Estonian	Study-wide	4480	T=0.1911	C=0.8089
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.1622	C=0.8378
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.1607	C=0.8393
KOREAN population from KRGDB	KOREAN	Study-wide	2930	T=0.7034	C=0.2966
HGDP-CEPH-db Supplement 1	Global	Study-wide	2084	T=0.4573	C=0.5427
HGDP-CEPH-db Supplement 1	Est_Asia	Sub	470	T=0.749	C=0.251
HGDP-CEPH-db Supplement 1	Central_South_Asia	Sub	414	T=0.316	C=0.684
HGDP-CEPH-db Supplement 1	Middle_Est	Sub	350	T=0.283	C=0.717
HGDP-CEPH-db Supplement 1	Europe	Sub	320	T=0.178	C=0.822
HGDP-CEPH-db Supplement 1	Africa	Sub	242	T=0.566	C=0.434
HGDP-CEPH-db Supplement 1	America	Sub	216	T=0.667	C=0.333
HGDP-CEPH-db Supplement 1	Oceania	Sub	72	T=0.46	C=0.54
HapMap	Global	Study-wide	1890	T=0.4259	C=0.5741
HapMap	American	Sub	770	T=0.392	C=0.608
HapMap	African	Sub	690	T=0.400	C=0.600
HapMap	Asian	Sub	254	T=0.728	C=0.272
HapMap	Europe	Sub	176	T=0.239	C=0.761
Genome of the Netherlands Release 5	Genome of the Netherlands	Study-wide	998	T=0.144	C=0.856
CNV burdens in cranial meningiomas	Global	Study-wide	786	T=0.720	C=0.280
CNV burdens in cranial meningiomas	CRM	Sub	786	T=0.720	C=0.280
Northern Sweden	ACPOP	Study-wide	600	T=0.147	C=0.853
SGDP_PRJ	Global	Study-wide	430	T=0.291	C=0.709
Qatari	Global	Study-wide	216	T=0.375	C=0.625
A Vietnamese Genetic Variation Database	Global	Study-wide	216	T=0.806	C=0.194
Ancient Sardinia genome-wide 1240k capture data generation and analysis	Global	Study-wide	54	T=0.30	C=0.70
Siberian	Global	Study-wide	42	T=0.21	C=0.79
The Danish reference pan genome	Danish	Study-wide	40	T=0.25	C=0.75

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements

Sequence name	Change
GRCh38.p14 chr 4	NC_000004.12:g.110744627T>C
GRCh37.p13 chr 4	NC_000004.11:g.111665783T>C

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement	T=	C
GRCh38.p14 chr 4	NC_000004.12:g.110744627=	NC_000004.12:g.110744627T>C
GRCh37.p13 chr 4	NC_000004.11:g.111665783=	NC_000004.11:g.111665783T>C

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

138 SubSNP, 23 Frequency submissions

No	Submitter	Submission ID	Date (Build)
1	SC_JCM	ss3710252	Sep 28, 2001 (100)
2	CSHL-HAPMAP	ss17009201	Feb 27, 2004 (120)
3	SSAHASNP	ss22144851	Apr 05, 2004 (121)
4	PERLEGEN	ss23337627	Sep 20, 2004 (123)
5	ILLUMINA	ss65818588	Oct 13, 2006 (127)
6	ILLUMINA	ss66557777	Nov 29, 2006 (127)
7	ILLUMINA	ss67264787	Nov 29, 2006 (127)
8	ILLUMINA	ss67664502	Nov 29, 2006 (127)
9	ILLUMINA	ss70743182	May 24, 2008 (130)
10	ILLUMINA	ss71314460	May 16, 2007 (127)
11	ILLUMINA	ss75229071	Dec 06, 2007 (129)
12	HGSV	ss77317336	Dec 06, 2007 (129)
13	ILLUMINA	ss79141664	Dec 15, 2007 (130)
14	KRIBB_YJKIM	ss84064044	Dec 15, 2007 (130)
15	BCMHGSC_JDW	ss92728647	Mar 24, 2008 (129)
16	HUMANGENOME_JCVI	ss98852872	Feb 04, 2009 (130)
17	BGI	ss104105976	Dec 01, 2009 (131)
18	1000GENOMES	ss108225714	Jan 23, 2009 (130)
19	1000GENOMES	ss110400144	Jan 24, 2009 (130)
20	ILLUMINA-UK	ss117140829	Feb 14, 2009 (130)
21	ILLUMINA	ss122074160	Dec 01, 2009 (131)
22	ENSEMBL	ss135185924	Dec 01, 2009 (131)
23	ENSEMBL	ss139818729	Dec 01, 2009 (131)
24	ILLUMINA	ss154224983	Dec 01, 2009 (131)
25	ILLUMINA	ss159401487	Dec 01, 2009 (131)
26	ILLUMINA	ss160565368	Dec 01, 2009 (131)
27	COMPLETE_GENOMICS	ss162439903	Jul 04, 2010 (132)
28	COMPLETE_GENOMICS	ss164064422	Jul 04, 2010 (132)
29	COMPLETE_GENOMICS	ss167029620	Jul 04, 2010 (132)
30	ILLUMINA	ss171326331	Jul 04, 2010 (132)
31	ILLUMINA	ss173413992	Jul 04, 2010 (132)
32	BUSHMAN	ss199015799	Jul 04, 2010 (132)
33	BCM-HGSC-SUB	ss206265777	Jul 04, 2010 (132)
34	1000GENOMES	ss221139573	Jul 14, 2010 (132)
35	1000GENOMES	ss232544221	Jul 14, 2010 (132)
36	1000GENOMES	ss239802293	Jul 15, 2010 (132)
37	BL	ss253425314	May 09, 2011 (134)
38	GMI	ss277873788	May 04, 2012 (137)
39	GMI	ss284981389	Apr 25, 2013 (138)
40	PJP	ss293161537	May 09, 2011 (134)
41	ILLUMINA	ss480622522	May 04, 2012 (137)
42	ILLUMINA	ss480637298	May 04, 2012 (137)
43	ILLUMINA	ss481475684	Sep 08, 2015 (146)
44	ILLUMINA	ss485106390	May 04, 2012 (137)
45	ILLUMINA	ss537111082	Sep 08, 2015 (146)
46	TISHKOFF	ss557770622	Apr 25, 2013 (138)
47	SSMP	ss651573184	Apr 25, 2013 (138)
48	ILLUMINA	ss778874704	Sep 08, 2015 (146)
49	ILLUMINA	ss782999479	Sep 08, 2015 (146)
50	ILLUMINA	ss783960020	Sep 08, 2015 (146)
51	ILLUMINA	ss825472182	Jul 19, 2016 (147)
52	ILLUMINA	ss832256543	Sep 08, 2015 (146)
53	ILLUMINA	ss832913201	Jul 13, 2019 (153)
54	ILLUMINA	ss834335650	Sep 08, 2015 (146)
55	EVA-GONL	ss980535141	Aug 21, 2014 (142)
56	JMKIDD_LAB	ss1071848217	Aug 21, 2014 (142)
57	1000GENOMES	ss1311289804	Aug 21, 2014 (142)
58	DDI	ss1430006733	Apr 01, 2015 (144)
59	EVA_GENOME_DK	ss1580718442	Apr 01, 2015 (144)
60	EVA_DECODE	ss1590040166	Apr 01, 2015 (144)
61	EVA_UK10K_ALSPAC	ss1610903936	Apr 01, 2015 (144)
62	EVA_UK10K_TWINSUK	ss1653897969	Apr 01, 2015 (144)
63	EVA_SVP	ss1712698277	Apr 01, 2015 (144)
64	ILLUMINA	ss1752492521	Sep 08, 2015 (146)
65	HAMMER_LAB	ss1802014120	Sep 08, 2015 (146)
66	WEILL_CORNELL_DGM	ss1923773613	Feb 12, 2016 (147)
67	ILLUMINA	ss1958712484	Feb 12, 2016 (147)
68	GENOMED	ss1969834728	Jul 19, 2016 (147)
69	JJLAB	ss2022470918	Sep 14, 2016 (149)
70	ILLUMINA	ss2094816269	Dec 20, 2016 (150)
71	ILLUMINA	ss2095147687	Dec 20, 2016 (150)
72	USC_VALOUEV	ss2150601259	Dec 20, 2016 (150)
73	HUMAN_LONGEVITY	ss2266072596	Dec 20, 2016 (150)
74	SYSTEMSBIOZJU	ss2625733489	Nov 08, 2017 (151)
75	ILLUMINA	ss2634163299	Nov 08, 2017 (151)
76	ILLUMINA	ss2635136164	Nov 08, 2017 (151)
77	GRF	ss2706080595	Nov 08, 2017 (151)
78	GNOMAD	ss2813751964	Nov 08, 2017 (151)
79	SWEGEN	ss2995337795	Nov 08, 2017 (151)
80	ILLUMINA	ss3022405115	Nov 08, 2017 (151)
81	BIOINF_KMB_FNS_UNIBA	ss3025010959	Nov 08, 2017 (151)
82	CSHL	ss3345897513	Nov 08, 2017 (151)
83	ILLUMINA	ss3629041091	Oct 12, 2018 (152)
84	ILLUMINA	ss3632097166	Oct 12, 2018 (152)
85	ILLUMINA	ss3633345520	Oct 12, 2018 (152)
86	ILLUMINA	ss3634064898	Oct 12, 2018 (152)
87	ILLUMINA	ss3634966339	Oct 12, 2018 (152)
88	ILLUMINA	ss3635747585	Oct 12, 2018 (152)
89	ILLUMINA	ss3636671009	Oct 12, 2018 (152)
90	ILLUMINA	ss3637500129	Oct 12, 2018 (152)
91	ILLUMINA	ss3638505724	Oct 12, 2018 (152)
92	ILLUMINA	ss3639255089	Oct 12, 2018 (152)
93	ILLUMINA	ss3639649079	Oct 12, 2018 (152)
94	ILLUMINA	ss3640673632	Oct 12, 2018 (152)
95	ILLUMINA	ss3643455620	Oct 12, 2018 (152)
96	URBANLAB	ss3647817773	Oct 12, 2018 (152)
97	ILLUMINA	ss3652892655	Oct 12, 2018 (152)
98	ILLUMINA	ss3652892656	Oct 12, 2018 (152)
99	EGCUT_WGS	ss3663237941	Jul 13, 2019 (153)
100	EVA_DECODE	ss3712809085	Jul 13, 2019 (153)
101	ILLUMINA	ss3726161669	Jul 13, 2019 (153)
102	ACPOP	ss3731490943	Jul 13, 2019 (153)
103	ILLUMINA	ss3745266597	Jul 13, 2019 (153)
104	EVA	ss3762256297	Jul 13, 2019 (153)
105	PAGE_CC	ss3771147012	Jul 13, 2019 (153)
106	ILLUMINA	ss3772761099	Jul 13, 2019 (153)
107	PACBIO	ss3784822050	Jul 13, 2019 (153)
108	PACBIO	ss3790263493	Jul 13, 2019 (153)
109	PACBIO	ss3795138865	Jul 13, 2019 (153)
110	KHV_HUMAN_GENOMES	ss3805405212	Jul 13, 2019 (153)
111	EVA	ss3828740928	Apr 26, 2020 (154)
112	EVA	ss3837812544	Apr 26, 2020 (154)
113	EVA	ss3843251312	Apr 26, 2020 (154)
114	HGDP	ss3847761118	Apr 26, 2020 (154)
115	SGDP_PRJ	ss3859773128	Apr 26, 2020 (154)
116	KRGDB	ss3906062358	Apr 26, 2020 (154)
117	EVA	ss3984533318	Apr 26, 2021 (155)
118	EVA	ss3985089376	Apr 26, 2021 (155)
119	EVA	ss4017163110	Apr 26, 2021 (155)
120	TOPMED	ss4627404049	Apr 26, 2021 (155)
121	TOMMO_GENOMICS	ss5167419767	Apr 26, 2021 (155)
122	1000G_HIGH_COVERAGE	ss5260559289	Oct 13, 2022 (156)
123	EVA	ss5314982449	Oct 13, 2022 (156)
124	EVA	ss5351465899	Oct 13, 2022 (156)
125	HUGCELL_USP	ss5459171508	Oct 13, 2022 (156)
126	1000G_HIGH_COVERAGE	ss5542368214	Oct 13, 2022 (156)
127	SANFORD_IMAGENETICS	ss5624564628	Oct 13, 2022 (156)
128	SANFORD_IMAGENETICS	ss5635819736	Oct 13, 2022 (156)
129	TOMMO_GENOMICS	ss5702248343	Oct 13, 2022 (156)
130	EVA	ss5799624063	Oct 13, 2022 (156)
131	YY_MCH	ss5805418844	Oct 13, 2022 (156)
132	EVA	ss5844529368	Oct 13, 2022 (156)
133	EVA	ss5847249010	Oct 13, 2022 (156)
134	EVA	ss5848021628	Oct 13, 2022 (156)
135	EVA	ss5854386948	Oct 13, 2022 (156)
136	EVA	ss5864986222	Oct 13, 2022 (156)
137	EVA	ss5964219980	Oct 13, 2022 (156)
138	EVA	ss5979711054	Oct 13, 2022 (156)
139	1000Genomes	NC_000004.11 - 111665783	Oct 12, 2018 (152)
140	1000Genomes_30x	NC_000004.12 - 110744627	Oct 13, 2022 (156)
141	The Avon Longitudinal Study of Parents and Children	NC_000004.11 - 111665783	Oct 12, 2018 (152)
142	Genetic variation in the Estonian population	NC_000004.11 - 111665783	Oct 12, 2018 (152)
143	The Danish reference pan genome	NC_000004.11 - 111665783	Apr 26, 2020 (154)
144	gnomAD - Genomes	NC_000004.12 - 110744627	Apr 26, 2021 (155)
145	Genome of the Netherlands Release 5	NC_000004.11 - 111665783	Apr 26, 2020 (154)
146	HGDP-CEPH-db Supplement 1	NC_000004.10 - 111885232	Apr 26, 2020 (154)
147	HapMap	NC_000004.12 - 110744627	Apr 26, 2020 (154)
148	KOREAN population from KRGDB	NC_000004.11 - 111665783	Apr 26, 2020 (154)
149	Northern Sweden	NC_000004.11 - 111665783	Jul 13, 2019 (153)
150	The PAGE Study	NC_000004.12 - 110744627	Jul 13, 2019 (153)
151	Ancient Sardinia genome-wide 1240k capture data generation and analysis	NC_000004.11 - 111665783	Apr 26, 2021 (155)
152	CNV burdens in cranial meningiomas	NC_000004.11 - 111665783	Apr 26, 2021 (155)
153	Qatari	NC_000004.11 - 111665783	Apr 26, 2020 (154)
154	SGDP_PRJ	NC_000004.11 - 111665783	Apr 26, 2020 (154)
155	Siberian	NC_000004.11 - 111665783	Apr 26, 2020 (154)
156	8.3KJPN	NC_000004.11 - 111665783	Apr 26, 2021 (155)
157	14KJPN	NC_000004.12 - 110744627	Oct 13, 2022 (156)
158	TopMed	NC_000004.12 - 110744627	Apr 26, 2021 (155)
159	UK 10K study - Twins	NC_000004.11 - 111665783	Oct 12, 2018 (152)
160	A Vietnamese Genetic Variation Database	NC_000004.11 - 111665783	Jul 13, 2019 (153)
161	ALFA	NC_000004.12 - 110744627	Apr 26, 2021 (155)

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID	History Updated (Build)
rs58300178	May 24, 2008 (130)
rs386570953	Aug 21, 2014 (142)

Added to this RefSNP Cluster:

Submission IDs	Observation SPDI	Canonical SPDI	Source RSIDs
ss77317336, ss3639255089, ss3639649079	NC_000004.9:112023386:T:C	NC_000004.12:110744626:T:C	(self)
439010, ss92728647, ss108225714, ss110400144, ss117140829, ss162439903, ss164064422, ss167029620, ss199015799, ss206265777, ss253425314, ss277873788, ss284981389, ss293161537, ss480622522, ss825472182, ss1590040166, ss1712698277, ss2635136164, ss3643455620, ss3847761118	NC_000004.10:111885231:T:C	NC_000004.12:110744626:T:C	(self)
22743815, 12656268, 8976189, 6883381, 5596680, 13239752, 4775808, 315303, 82679, 5815543, 11790108, 3117613, 25389074, 12656268, 2781528, ss221139573, ss232544221, ss239802293, ss480637298, ss481475684, ss485106390, ss537111082, ss557770622, ss651573184, ss778874704, ss782999479, ss783960020, ss832256543, ss832913201, ss834335650, ss980535141, ss1071848217, ss1311289804, ss1430006733, ss1580718442, ss1610903936, ss1653897969, ss1752492521, ss1802014120, ss1923773613, ss1958712484, ss1969834728, ss2022470918, ss2094816269, ss2095147687, ss2150601259, ss2625733489, ss2634163299, ss2706080595, ss2813751964, ss2995337795, ss3022405115, ss3345897513, ss3629041091, ss3632097166, ss3633345520, ss3634064898, ss3634966339, ss3635747585, ss3636671009, ss3637500129, ss3638505724, ss3640673632, ss3652892655, ss3652892656, ss3663237941, ss3731490943, ss3745266597, ss3762256297, ss3772761099, ss3784822050, ss3790263493, ss3795138865, ss3828740928, ss3837812544, ss3859773128, ss3906062358, ss3984533318, ss3985089376, ss4017163110, ss5167419767, ss5314982449, ss5351465899, ss5624564628, ss5635819736, ss5799624063, ss5844529368, ss5847249010, ss5848021628, ss5964219980, ss5979711054	NC_000004.11:111665782:T:C	NC_000004.12:110744626:T:C	(self)
29894149, 161135753, 2684435, 368481, 36085447, 464781605, 9369128435, ss2266072596, ss3025010959, ss3647817773, ss3712809085, ss3726161669, ss3771147012, ss3805405212, ss3843251312, ss4627404049, ss5260559289, ss5459171508, ss5542368214, ss5702248343, ss5805418844, ss5854386948, ss5864986222	NC_000004.12:110744626:T:C	NC_000004.12:110744626:T:C	(self)
ss17009201, ss22144851	NT_016354.16:36160912:T:C	NC_000004.12:110744626:T:C	(self)
ss3710252, ss23337627, ss65818588, ss66557777, ss67264787, ss67664502, ss70743182, ss71314460, ss75229071, ss79141664, ss84064044, ss98852872, ss104105976, ss122074160, ss135185924, ss139818729, ss154224983, ss159401487, ss160565368, ss171326331, ss173413992	NT_016354.19:36213503:T:C	NC_000004.12:110744626:T:C	(self)

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

4 citations for rs2634073

PMID	Title	Author	Year	Journal
20031626	Variation in the 4q25 chromosomal locus predicts atrial fibrillation after coronary artery bypass graft surgery.	Body SC et al.	2009	Circulation. Cardiovascular genetics
20606429	Association of RS2200733 but not RS10033464 on 4q25 with atrial fibrillation based on the recessive model in a Taiwanese population.	Lee KT et al.	2010	Cardiology
25494715	Incidence of dementia in relation to genetic variants at PITX2, ZFHX3, and ApoE ε4 in atrial fibrillation patients.	Rollo J et al.	2015	Pacing and clinical electrophysiology
28804107	Association of the Clinical and Genetic Factors With Superior Vena Cava Arrhythmogenicity in Atrial Fibrillation.	Ebana Y et al.	2017	Circulation journal

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:

Select flank length:

Genomic regions, transcripts, and products
Top▲ Help
NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

Reference SNP (rs) Report

rs2634073