Name: rs25486
Published: September 21, 2022
License: Open Access

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs25486

Current Build 156

Released September 21, 2022

Organism: Homo sapiens
Position: chr19:43551746 (GRCh38.p14) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
Alleles: C>G / C>T
Variation Type: SNV Single Nucleotide Variation
Frequency: C=0.308501 (81657/264690, TOPMED)
C=0.311199 (43523/139856, GnomAD)
C=0.26661 (20982/78700, PAGE_STUDY) (+ 19 more)
C=0.26336 (7440/28250, 14KJPN)
C=0.31789 (8030/25260, ALFA)
C=0.25692 (4306/16760, 8.3KJPN)
C=0.2833 (1814/6404, 1000G_30x)
C=0.2829 (1417/5008, 1000G)
C=0.3246 (1454/4480, Estonian)
C=0.3542 (1365/3854, ALSPAC)
C=0.3743 (1388/3708, TWINSUK)
C=0.2468 (723/2930, KOREAN)
C=0.2791 (528/1892, HapMap)
C=0.2489 (456/1832, Korea1K)
C=0.352 (351/998, GoNL)
C=0.243 (146/600, NorthernSweden)
C=0.322 (172/534, MGP)
C=0.334 (177/530, Vietnamese)
C=0.215 (108/502, SGDP_PRJ)
C=0.218 (47/216, Qatari)
C=0.17 (7/42, Siberian)
C=0.25 (10/40, GENOME_DK)

Clinical Significance: Not Reported in ClinVar
Gene : Consequence: XRCC1 : Intron Variant
Publications: 5 citations
Genomic View: See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20230706150541

Population	Group	Sample Size	Ref Allele	Alt Allele
Total	Global	25260	C=0.31789	G=0.00000, T=0.68211
European	Sub	16168	C=0.35335	G=0.00000, T=0.64665
African	Sub	6692	C=0.2316	G=0.0000, T=0.7684
African Others	Sub	210	C=0.219	G=0.000, T=0.781
African American	Sub	6482	C=0.2320	G=0.0000, T=0.7680
Asian	Sub	158	C=0.304	G=0.000, T=0.696
East Asian	Sub	130	C=0.300	G=0.000, T=0.700
Other Asian	Sub	28	C=0.32	G=0.00, T=0.68
Latin American 1	Sub	168	C=0.310	G=0.000, T=0.690
Latin American 2	Sub	670	C=0.278	G=0.000, T=0.722
South Asian	Sub	104	C=0.346	G=0.000, T=0.654
Other	Sub	1300	C=0.3423	G=0.0000, T=0.6577

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

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Study	Population	Group	Sample Size	Ref Allele	Alt Allele
TopMed	Global	Study-wide	264690	C=0.308501	T=0.691499
gnomAD - Genomes	Global	Study-wide	139856	C=0.311199	T=0.688801
gnomAD - Genomes	European	Sub	75766	C=0.35086	T=0.64914
gnomAD - Genomes	African	Sub	41876	C=0.23056	T=0.76944
gnomAD - Genomes	American	Sub	13626	C=0.32232	T=0.67768
gnomAD - Genomes	Ashkenazi Jewish	Sub	3320	C=0.4202	T=0.5798
gnomAD - Genomes	East Asian	Sub	3124	C=0.2772	T=0.7228
gnomAD - Genomes	Other	Sub	2144	C=0.2948	T=0.7052
The PAGE Study	Global	Study-wide	78700	C=0.26661	T=0.73339
The PAGE Study	AfricanAmerican	Sub	32514	C=0.23614	T=0.76386
The PAGE Study	Mexican	Sub	10810	C=0.26984	T=0.73016
The PAGE Study	Asian	Sub	8318	C=0.2676	T=0.7324
The PAGE Study	PuertoRican	Sub	7918	C=0.2992	T=0.7008
The PAGE Study	NativeHawaiian	Sub	4534	C=0.2936	T=0.7064
The PAGE Study	Cuban	Sub	4230	C=0.3189	T=0.6811
The PAGE Study	Dominican	Sub	3828	C=0.2615	T=0.7385
The PAGE Study	CentralAmerican	Sub	2450	C=0.3143	T=0.6857
The PAGE Study	SouthAmerican	Sub	1982	C=0.3285	T=0.6715
The PAGE Study	NativeAmerican	Sub	1260	C=0.3024	T=0.6976
The PAGE Study	SouthAsian	Sub	856	C=0.361	T=0.639
14KJPN	JAPANESE	Study-wide	28250	C=0.26336	T=0.73664
Allele Frequency Aggregator	Total	Global	25260	C=0.31789	G=0.00000, T=0.68211
Allele Frequency Aggregator	European	Sub	16168	C=0.35335	G=0.00000, T=0.64665
Allele Frequency Aggregator	African	Sub	6692	C=0.2316	G=0.0000, T=0.7684
Allele Frequency Aggregator	Other	Sub	1300	C=0.3423	G=0.0000, T=0.6577
Allele Frequency Aggregator	Latin American 2	Sub	670	C=0.278	G=0.000, T=0.722
Allele Frequency Aggregator	Latin American 1	Sub	168	C=0.310	G=0.000, T=0.690
Allele Frequency Aggregator	Asian	Sub	158	C=0.304	G=0.000, T=0.696
Allele Frequency Aggregator	South Asian	Sub	104	C=0.346	G=0.000, T=0.654
8.3KJPN	JAPANESE	Study-wide	16760	C=0.25692	T=0.74308
1000Genomes_30x	Global	Study-wide	6404	C=0.2833	T=0.7167
1000Genomes_30x	African	Sub	1786	C=0.1870	T=0.8130
1000Genomes_30x	Europe	Sub	1266	C=0.3799	T=0.6201
1000Genomes_30x	South Asian	Sub	1202	C=0.3386	T=0.6614
1000Genomes_30x	East Asian	Sub	1170	C=0.2470	T=0.7530
1000Genomes_30x	American	Sub	980	C=0.309	T=0.691
1000Genomes	Global	Study-wide	5008	C=0.2829	T=0.7171
1000Genomes	African	Sub	1322	C=0.1853	T=0.8147
1000Genomes	East Asian	Sub	1008	C=0.2431	T=0.7569
1000Genomes	Europe	Sub	1006	C=0.3638	T=0.6362
1000Genomes	South Asian	Sub	978	C=0.345	T=0.655
1000Genomes	American	Sub	694	C=0.323	T=0.677
Genetic variation in the Estonian population	Estonian	Study-wide	4480	C=0.3246	T=0.6754
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.3542	T=0.6458
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.3743	T=0.6257
KOREAN population from KRGDB	KOREAN	Study-wide	2930	C=0.2468	G=0.0000, T=0.7532
HapMap	Global	Study-wide	1892	C=0.2791	T=0.7209
HapMap	American	Sub	770	C=0.353	T=0.647
HapMap	African	Sub	692	C=0.182	T=0.818
HapMap	Asian	Sub	254	C=0.264	T=0.736
HapMap	Europe	Sub	176	C=0.358	T=0.642
Korean Genome Project	KOREAN	Study-wide	1832	C=0.2489	T=0.7511
Genome of the Netherlands Release 5	Genome of the Netherlands	Study-wide	998	C=0.352	T=0.648
Northern Sweden	ACPOP	Study-wide	600	C=0.243	T=0.757
Medical Genome Project healthy controls from Spanish population	Spanish controls	Study-wide	534	C=0.322	T=0.678
A Vietnamese Genetic Variation Database	Global	Study-wide	530	C=0.334	T=0.666
SGDP_PRJ	Global	Study-wide	502	C=0.215	T=0.785
Qatari	Global	Study-wide	216	C=0.218	T=0.782
Siberian	Global	Study-wide	42	C=0.17	T=0.83
The Danish reference pan genome	Danish	Study-wide	40	C=0.25	T=0.75

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements

Sequence name	Change
GRCh38.p14 chr 19	NC_000019.10:g.43551746C>G
GRCh38.p14 chr 19	NC_000019.10:g.43551746C>T
GRCh37.p13 chr 19	NC_000019.9:g.44055898C>G
GRCh37.p13 chr 19	NC_000019.9:g.44055898C>T
XRCC1 RefSeqGene (LRG_784)	NG_033799.1:g.28833G>C
XRCC1 RefSeqGene (LRG_784)	NG_033799.1:g.28833G>A

Gene: XRCC1, X-ray repair cross complementing 1 (minus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
XRCC1 transcript	NM_006297.3:c.1083-59G>C	N/A	Intron Variant

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement	C=	G	T
GRCh38.p14 chr 19	NC_000019.10:g.43551746=	NC_000019.10:g.43551746C>G	NC_000019.10:g.43551746C>T
GRCh37.p13 chr 19	NC_000019.9:g.44055898=	NC_000019.9:g.44055898C>G	NC_000019.9:g.44055898C>T
XRCC1 RefSeqGene (LRG_784)	NG_033799.1:g.28833=	NG_033799.1:g.28833G>C	NG_033799.1:g.28833G>A
XRCC1 transcript	NM_006297.2:c.1083-59=	NM_006297.2:c.1083-59G>C	NM_006297.2:c.1083-59G>A
XRCC1 transcript	NM_006297.3:c.1083-59=	NM_006297.3:c.1083-59G>C	NM_006297.3:c.1083-59G>A

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

116 SubSNP, 22 Frequency submissions

No	Submitter	Submission ID	Date (Build)
1	OEFNER	ss28205	Feb 22, 2000 (71)
2	TSC-CSHL	ss92684	Oct 13, 2000 (123)
3	YUSUKE	ss3206942	Sep 28, 2001 (100)
4	SC_JCM	ss3786941	Sep 28, 2001 (100)
5	EGP_SNPS	ss4473995	Jul 03, 2002 (106)
6	SNP500CANCER	ss5586976	Jul 02, 2003 (116)
7	WI_SSAHASNP	ss12473263	Jul 11, 2003 (116)
8	CSHL-HAPMAP	ss16809505	Feb 27, 2004 (120)
9	SSAHASNP	ss21552793	Apr 05, 2004 (121)
10	ABI	ss44174858	Mar 14, 2006 (126)
11	SI_EXO	ss52076075	Oct 16, 2006 (127)
12	ILLUMINA	ss75144638	Dec 06, 2007 (129)
13	CGM_KYOTO	ss76863648	Dec 06, 2007 (129)
14	HGSV	ss81533125	Dec 15, 2007 (130)
15	HGSV	ss84429487	Dec 15, 2007 (130)
16	BCMHGSC_JDW	ss90981938	Mar 24, 2008 (129)
17	HUMANGENOME_JCVI	ss96268643	Feb 05, 2009 (130)
18	BGI	ss106056340	Feb 05, 2009 (130)
19	1000GENOMES	ss111404495	Jan 25, 2009 (130)
20	1000GENOMES	ss115168772	Jan 25, 2009 (130)
21	ILLUMINA-UK	ss117713220	Feb 14, 2009 (130)
22	KRIBB_YJKIM	ss119339872	Dec 01, 2009 (131)
23	ENSEMBL	ss132768450	Dec 01, 2009 (131)
24	ENSEMBL	ss137687946	Dec 01, 2009 (131)
25	GMI	ss155923765	Dec 01, 2009 (131)
26	COMPLETE_GENOMICS	ss168227477	Jul 04, 2010 (132)
27	COMPLETE_GENOMICS	ss169801697	Jul 04, 2010 (132)
28	ILLUMINA	ss173387699	Jul 04, 2010 (132)
29	BUSHMAN	ss203762256	Jul 04, 2010 (132)
30	BCM-HGSC-SUB	ss208394648	Jul 04, 2010 (132)
31	1000GENOMES	ss228151067	Jul 14, 2010 (132)
32	1000GENOMES	ss237685542	Jul 15, 2010 (132)
33	1000GENOMES	ss243889122	Jul 15, 2010 (132)
34	BL	ss255689620	May 09, 2011 (134)
35	GMI	ss283219243	May 04, 2012 (137)
36	GMI	ss287386128	Apr 25, 2013 (138)
37	PJP	ss292181893	May 09, 2011 (134)
38	CLINSEQ_SNP	ss491769034	May 04, 2012 (137)
39	ILLUMINA	ss537102833	Sep 08, 2015 (146)
40	TISHKOFF	ss566000622	Apr 25, 2013 (138)
41	SSMP	ss661867764	Apr 25, 2013 (138)
42	JMKIDD_LAB	ss974506465	Aug 21, 2014 (142)
43	EVA-GONL	ss994328877	Aug 21, 2014 (142)
44	JMKIDD_LAB	ss1067590311	Aug 21, 2014 (142)
45	JMKIDD_LAB	ss1081922933	Aug 21, 2014 (142)
46	1000GENOMES	ss1363287679	Aug 21, 2014 (142)
47	DDI	ss1428410472	Apr 01, 2015 (144)
48	EVA_GENOME_DK	ss1578649467	Apr 01, 2015 (144)
49	EVA_UK10K_ALSPAC	ss1638023872	Apr 01, 2015 (144)
50	EVA_UK10K_TWINSUK	ss1681017905	Apr 01, 2015 (144)
51	EVA_DECODE	ss1698383647	Apr 01, 2015 (144)
52	EVA_MGP	ss1711516491	Apr 01, 2015 (144)
53	EVA_SVP	ss1713664103	Apr 01, 2015 (144)
54	HAMMER_LAB	ss1809320827	Sep 08, 2015 (146)
55	WEILL_CORNELL_DGM	ss1937824540	Feb 12, 2016 (147)
56	ILLUMINA	ss1959867564	Feb 12, 2016 (147)
57	GENOMED	ss1968648433	Jul 19, 2016 (147)
58	JJLAB	ss2029689934	Sep 14, 2016 (149)
59	USC_VALOUEV	ss2158231660	Dec 20, 2016 (150)
60	HUMAN_LONGEVITY	ss2225938835	Dec 20, 2016 (150)
61	SYSTEMSBIOZJU	ss2629341306	Nov 08, 2017 (151)
62	ILLUMINA	ss2635083762	Nov 08, 2017 (151)
63	GRF	ss2702844272	Nov 08, 2017 (151)
64	GNOMAD	ss2963218777	Nov 08, 2017 (151)
65	SWEGEN	ss3017523534	Nov 08, 2017 (151)
66	ILLUMINA	ss3021909425	Nov 08, 2017 (151)
67	BIOINF_KMB_FNS_UNIBA	ss3028674988	Nov 08, 2017 (151)
68	CSHL	ss3352315314	Nov 08, 2017 (151)
69	ILLUMINA	ss3627938441	Oct 12, 2018 (152)
70	ILLUMINA	ss3638229064	Oct 12, 2018 (152)
71	ILLUMINA	ss3643201733	Oct 12, 2018 (152)
72	OMUKHERJEE_ADBS	ss3646537916	Oct 12, 2018 (152)
73	URBANLAB	ss3650923073	Oct 12, 2018 (152)
74	ILLUMINA	ss3652335434	Oct 12, 2018 (152)
75	EGCUT_WGS	ss3684271982	Jul 13, 2019 (153)
76	EVA_DECODE	ss3702825215	Jul 13, 2019 (153)
77	ILLUMINA	ss3725731782	Jul 13, 2019 (153)
78	ACPOP	ss3743063342	Jul 13, 2019 (153)
79	EVA	ss3756100050	Jul 13, 2019 (153)
80	PAGE_CC	ss3772015561	Jul 13, 2019 (153)
81	PACBIO	ss3788538040	Jul 13, 2019 (153)
82	PACBIO	ss3793446840	Jul 13, 2019 (153)
83	PACBIO	ss3798333710	Jul 13, 2019 (153)
84	KHV_HUMAN_GENOMES	ss3821348046	Jul 13, 2019 (153)
85	EVA	ss3825937632	Apr 27, 2020 (154)
86	EVA	ss3835475546	Apr 27, 2020 (154)
87	EVA	ss3841360323	Apr 27, 2020 (154)
88	EVA	ss3846866423	Apr 27, 2020 (154)
89	SGDP_PRJ	ss3888283706	Apr 27, 2020 (154)
90	KRGDB	ss3938407465	Apr 27, 2020 (154)
91	KOGIC	ss3981414464	Apr 27, 2020 (154)
92	FSA-LAB	ss3984156049	Apr 26, 2021 (155)
93	EVA	ss3986800847	Apr 26, 2021 (155)
94	TOPMED	ss5075843397	Apr 26, 2021 (155)
95	TOMMO_GENOMICS	ss5227904412	Apr 26, 2021 (155)
96	EVA	ss5237247794	Apr 26, 2021 (155)
97	1000G_HIGH_COVERAGE	ss5307359413	Oct 16, 2022 (156)
98	EVA	ss5435026299	Oct 16, 2022 (156)
99	HUGCELL_USP	ss5499859858	Oct 16, 2022 (156)
100	EVA	ss5512109622	Oct 16, 2022 (156)
101	1000G_HIGH_COVERAGE	ss5613141126	Oct 16, 2022 (156)
102	EVA	ss5623978180	Oct 16, 2022 (156)
103	EVA	ss5624091161	Oct 16, 2022 (156)
104	SANFORD_IMAGENETICS	ss5662454496	Oct 16, 2022 (156)
105	TOMMO_GENOMICS	ss5786584002	Oct 16, 2022 (156)
106	EVA	ss5800073478	Oct 16, 2022 (156)
107	EVA	ss5800223519	Oct 16, 2022 (156)
108	YY_MCH	ss5817627855	Oct 16, 2022 (156)
109	EVA	ss5840592445	Oct 16, 2022 (156)
110	EVA	ss5848494532	Oct 16, 2022 (156)
111	EVA	ss5852299669	Oct 16, 2022 (156)
112	EVA	ss5928217173	Oct 16, 2022 (156)
113	EVA	ss5936574294	Oct 16, 2022 (156)
114	EVA	ss5953864712	Oct 16, 2022 (156)
115	EVA	ss5981056371	Oct 16, 2022 (156)
116	EVA	ss5981312913	Oct 16, 2022 (156)
117	1000Genomes	NC_000019.9 - 44055898	Oct 12, 2018 (152)
118	1000Genomes_30x	NC_000019.10 - 43551746	Oct 16, 2022 (156)
119	The Avon Longitudinal Study of Parents and Children	NC_000019.9 - 44055898	Oct 12, 2018 (152)
120	Genetic variation in the Estonian population	NC_000019.9 - 44055898	Oct 12, 2018 (152)
121	The Danish reference pan genome	NC_000019.9 - 44055898	Apr 27, 2020 (154)
122	gnomAD - Genomes	NC_000019.10 - 43551746	Apr 26, 2021 (155)
123	Genome of the Netherlands Release 5	NC_000019.9 - 44055898	Apr 27, 2020 (154)
124	HapMap	NC_000019.10 - 43551746	Apr 27, 2020 (154)
125	KOREAN population from KRGDB	NC_000019.9 - 44055898	Apr 27, 2020 (154)
126	Korean Genome Project	NC_000019.10 - 43551746	Apr 27, 2020 (154)
127	Medical Genome Project healthy controls from Spanish population	NC_000019.9 - 44055898	Apr 27, 2020 (154)
128	Northern Sweden	NC_000019.9 - 44055898	Jul 13, 2019 (153)
129	The PAGE Study	NC_000019.10 - 43551746	Jul 13, 2019 (153)
130	Qatari	NC_000019.9 - 44055898	Apr 27, 2020 (154)
131	SGDP_PRJ	NC_000019.9 - 44055898	Apr 27, 2020 (154)
132	Siberian	NC_000019.9 - 44055898	Apr 27, 2020 (154)
133	8.3KJPN	NC_000019.9 - 44055898	Apr 26, 2021 (155)
134	14KJPN	NC_000019.10 - 43551746	Oct 16, 2022 (156)
135	TopMed	NC_000019.10 - 43551746	Apr 26, 2021 (155)
136	UK 10K study - Twins	NC_000019.9 - 44055898	Oct 12, 2018 (152)
137	A Vietnamese Genetic Variation Database	NC_000019.9 - 44055898	Jul 13, 2019 (153)
138	ALFA	NC_000019.10 - 43551746	Apr 26, 2021 (155)

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID	History Updated (Build)
rs1076856	Sep 24, 2004 (123)
rs59368077	May 25, 2008 (130)

Added to this RefSNP Cluster:

Submission IDs	Observation SPDI	Canonical SPDI	Source RSIDs
45584859, ss3938407465	NC_000019.9:44055897:C:G	NC_000019.10:43551745:C:G	(self)
6126298195	NC_000019.10:43551745:C:G	NC_000019.10:43551745:C:G	(self)
ss81533125, ss84429487, ss90981938, ss111404495, ss115168772, ss117713220, ss168227477, ss169801697, ss203762256, ss208394648, ss255689620, ss283219243, ss287386128, ss292181893, ss491769034, ss1698383647, ss1713664103, ss2635083762, ss3643201733	NC_000019.8:48747737:C:T	NC_000019.10:43551745:C:T	(self)
76698536, 42471575, 30010230, 4831532, 18920789, 45584859, 632251, 16348207, 19866462, 40300686, 10748014, 85873719, 42471575, 9378987, ss228151067, ss237685542, ss243889122, ss537102833, ss566000622, ss661867764, ss974506465, ss994328877, ss1067590311, ss1081922933, ss1363287679, ss1428410472, ss1578649467, ss1638023872, ss1681017905, ss1711516491, ss1809320827, ss1937824540, ss1959867564, ss1968648433, ss2029689934, ss2158231660, ss2629341306, ss2702844272, ss2963218777, ss3017523534, ss3021909425, ss3352315314, ss3627938441, ss3638229064, ss3646537916, ss3652335434, ss3684271982, ss3743063342, ss3756100050, ss3788538040, ss3793446840, ss3798333710, ss3825937632, ss3835475546, ss3841360323, ss3888283706, ss3938407465, ss3984156049, ss3986800847, ss5227904412, ss5435026299, ss5512109622, ss5623978180, ss5624091161, ss5662454496, ss5800073478, ss5800223519, ss5840592445, ss5848494532, ss5936574294, ss5953864712, ss5981056371, ss5981312913	NC_000019.9:44055897:C:T	NC_000019.10:43551745:C:T	(self)
100667061, 540917323, 1699771, 37792465, 1237030, 120421106, 291389061, 6126298195, ss2225938835, ss3028674988, ss3650923073, ss3702825215, ss3725731782, ss3772015561, ss3821348046, ss3846866423, ss3981414464, ss5075843397, ss5237247794, ss5307359413, ss5499859858, ss5613141126, ss5786584002, ss5817627855, ss5852299669, ss5928217173	NC_000019.10:43551745:C:T	NC_000019.10:43551745:C:T	(self)
ss12473263, ss16809505, ss21552793, ss52076075	NT_011109.15:16324115:C:T	NC_000019.10:43551745:C:T	(self)
ss28205, ss92684, ss3206942, ss3786941, ss4473995, ss5586976, ss44174858, ss75144638, ss76863648, ss96268643, ss106056340, ss119339872, ss132768450, ss137687946, ss155923765, ss173387699	NT_011109.16:16324115:C:T	NC_000019.10:43551745:C:T	(self)

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

5 citations for rs25486

PMID	Title	Author	Year	Journal
18936436	Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994.	Chang MH et al.	2009	American journal of epidemiology
19029194	Base excision repair genes and risk of lung cancer among San Francisco Bay Area Latinos and African-Americans.	Chang JS et al.	2009	Carcinogenesis
21622940	Single-nucleotide polymorphisms in DNA repair genes and association with breast cancer risk in the web study.	Roberts MR et al.	2011	Carcinogenesis
23565320	DNA repair genotype and lung cancer risk in the beta-carotene and retinol efficacy trial.	Doherty JA et al.	2013	International journal of molecular epidemiology and genetics
30139066	Meta-Analysis of Polymorphic Variants Conferring Genetic Risk to Cervical Cancer in Indian Women Supports CYP1A1 as an Important Associated Locus.	Sengupta D et al.	2018	Asian Pacific journal of cancer prevention

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:

Select flank length:

Genomic regions, transcripts, and products
Top▲ Help
NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

Choose placement

dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

Reference SNP (rs) Report

rs25486