PMC

Pie chart representing the outcome of the qualitative efficacy analysis, with the green area representing no difference between men and women; the yellow area representing higher efficacy in women than in men; and the blue area representing higher efficacy in men than in women

Pie chart representing the outcomes of the qualitative gender analysis. Subgroup analysis of the retrieved drug data was performed for efficacy (purple), safety (green), and efficacy and safety (yellow). For a small proportion, no subgroup analysis was performed (red)

Pie chart representing the outcome of the qualitative safety analysis, with the purple area representing no difference between men and women, the red area representing more adverse events reported in women than in men, and the grey area representing more adverse events reported in men than in women

Bar graph representing the percentages of females participating in clinical trials (green bars) vs. the proportion of females with the disease, and the proportion for whom no gender was reported (yellow). The drugs are listed alphabetically, from A–L (A) and Li–Z (B)