PMC

Scatter plots showing individual correlations and differences of prostate D90, V100, and V150 values between iRUF/USD and CT/MRI. Linear regression lines (solid) as well as 45 degree reference line (dotted) for perfect correlation are overlaid. D90 is represented as the percentage dose to the prescribed dose.

Scatter plots showing individual correlations and differences of urethral D50, D30, and D5 values between iRUF/USD and CT/MRI. Linear regression lines (solid) as well as 45 degree reference line (dotted) for perfect correlation are overlaid. Values are represented as the percentage dose to the prescribed dose.

iRUF dosimetry workflow. Three-dimensional locations of implanted seeds are reconstructed (middle upper image) from three x-ray images taken with a mobile C-arm (left image), and are registered to TRUS volume (middle lower image). Dose distribution is computed based on the registered seeds and overlaid to the current TRUS volume with critical structure contours (right image).

iRUF image processing. (a) Original x-ray. (b) Automatic seed segmentation and fiducial detection. Yellow dots = segmented single seeds; red circles = segmented overlapped (clustered) seeds; green circles = detected fiducial points. (c) 3D reconstructed seed locations (blue dots). (d) TRUS image with registered seeds overlaid with the contours of the prostate (red), PTV (cyan), urethra (blue) and rectum (green).