PMC

Receiver operator characteristic curve for detecting an adverse outcome using MRI injury score. X-axis displays 1-Specificity. Y-axis displays sensitivity

MRI injury grade and neurodevelopmental outcomes by domain. a Box and whisker plot compares MRI injury grade with Bayley-III cognitive domain. X-axis displays MRI injury grade. Y-axis displays the individual Bayley-III domain. b Box and whisker plot compares MRI injury grade with Bayley-III motor domain. X-axis displays MRI injury grade. Y-axis displays the individual Bayley-III domain. c Box and whisker plot compares MRI injury grade with Bayley-III language domain. X-axis displays MRI injury grade. Y-axis displays the individual Bayley-III domain

MRI injury score and severity of developmental delay by domain. a Box and whisker plot compares MRI injury score with Bayley-III cognitive domain separated into categories by severity of neurodevelopmental impairment. X-axis displays MRI injury score. Y-axis displays the individual Bayley-III domain neurodevelopmental impairment categories. b Box and whisker plot compares MRI injury score with Bayley-III motor domain separated into categories by severity of neurodevelopmental impairment. X-axis displays MRI injury score. Y-axis displays the individual Bayley-III domain neurodevelopmental impairment categories. c Box and whisker plot compares MRI injury score with Bayley-III language domain separated into categories by severity of neurodevelopmental impairment. X-axis displays MRI injury score. Y-axis displays the individual Bayley-III domain neurodevelopmental impairment categories

Examples of MRI regional scores. a T1-W image score of bilateral globus pallidus/putamen injury (2+2=4) (T1 score=4) (arrows indicate regions of globus pallidus/putamen injury) in a 9-day-old girl (gestational age of 40 weeks). b T2-W image score of bilateral globus pallidus/putamen injury (2+2=4) and bilateral cortical injury (1+1=2) (T2 score=6) (arrows indicate regions of globus pallidus/putamen and cortical injury) in an 11-day-old girl (gestational age 40 weeks)). c Diffusion-weighted MRI image of bilateral restriction in the white matter (1+1=2) (DWI score=2) (arrows indicate regions of white matter injury) in a 5-day-old girl (gestational age of 38 weeks). d T2-W image score of unilateral cerebellar injury (1) (T2 score=2) (arrow indicates region of cerebellar injury) in a 1-day-old girl (gestational age of 36 weeks). e T1-W image score of bilateral global pallidus/putamen (2+2=4) and thalamus injury (2+2=4) (T1 score=8) (arrows indicate regions of globus pallidus/putamen and thalamic injury) in a 10-day-old boy (gestational age of 40 weeks)