PMC

Cumulative incidence of second primary malignancies and overall survival of patients with or without second primary malignancies. (A) Cumulative incidence of SPM in 514 patients (309 males; 205 females); the estimated 7-year cumulative incidence was 6.3% and 8.5% in males and females, respectively; (B) Overall survival (OS) from CML diagnosis: 7-year OS was 43.6% in patients with SPM (n=30) and 89.9% in patients without SPM (n=484); P<0.001. (C) OS from SPM diagnosis (n=30): the median OS was 18 months, and the estimated 4-year OS was 42.3%