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Fig 5. Empirical progression rates observed in the NIA ADC longitudinal cohort as a function of predicted incidence.. From: Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.
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Fig 4. Annualized incidence rates showing the instantaneous hazard as a function of polygenic hazard score percentile and age.. From: Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.
Fig 2. Kaplan–Meier estimates and Cox proportional hazard model fits among APOE ε3/3 individuals in the ADGC Phase 1 dataset, excluding NIA ADC and ADNI samples.. From: Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.
Fig 3. Polygenic hazard score validation in ADGC Phase 2 cohort.. From: Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.
Fig 1. Kaplan–Meier estimates and Cox proportional hazard model fits from the ADGC Phase 1 case–control dataset, excluding NIA ADC and ADNI samples.. From: Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.
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