PMC

Serial course of IL-17A levels over the pre-study (retrospective) disease course in 18 patients with SLE

Factor matrix of the PCA for SLEDAI-2K (a) and SDI (b). Projection of 102 SLE patients, described by 26 variables (listed in and ) for the first two principal components, PC1 (x-axis) and PC2 (y-axis) as determined by PCA for disease activity [SLEDAI <3 = O, SLEDAI ≥3 = +] (a) and organ damage [SLICC-DI=0 = O, SLICC-DO > 0 = +] (b). The graphs provide quantitative information on the similarity of variables as determined by the PCA: the distance of the factor to the null represents the correlation of that factor to the system, i.e., SLEDAI-2K or SLICC-DI status. The shorter the distance between two or a cluster of factors, more similar their effects are on SLEDAI-2K or SLICC-DI (see Methods for a more detailed description)