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Fig. 4. Structure based design of MFQ-derivatives.. From: The antimalarial Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis.
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Fig. 1. MFQ inhibits cytosolic translation in P. falciparum.. From: The antimalarial Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis.
Fig. 2. MFQ interacts with the GTPase-associated center of the P. falciparum large ribosomal subunit.. From: The antimalarial Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis.
Fig. 3. The primary binding site for (+)-MFQ.. From: The antimalarial Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis.
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