PMC

Symmetry-adapted perturbation theory results of the RS_CX3-CH3_CX3-CH3_2.00 system.

Representative XPS spectra of (A) N 1s, (B) C 1s, and (C) O 1s for the monolayers of oligopeptide.

Gaussian 09 output of the RS_CH3_CH3_2.00 system (methyl radical dimer with C-C distance of 2.00 Å) with an open shell singlet state.

Optical microscope image of the GaN-based Hall device. The distance between the S and D electrodes is 500 μm, and the distance between the Hall electrodes (H1 and H2) is 40 μm.

Grazing angle attenuated total reflectance Fourier transform IR (GATR-FTIR) spectra of (A) 11-mercaptoundecanoic acid, (B) SHCH₂CH₂CO-{Ala-Aib}₅-COOH, and (C) SHCH₂CH₂CO-{Ala-Aib}₇-COOH monolayers on GaN.

Calibration curve of the Hall device. Hall voltage (V_H) is plotted vs. external magnetic field (H) at room temperature. A slight asymmetry exists because of asymmetry in the position of the Hall electrodes.

An example illustrating the interaction of an enzyme and its substrate. Left shows a subunit of citrate lyase from Mycobacterium tuberculosis with a bound ligand. Right, an expanded view of the binding pocket of citrate lyase, illustrates the interaction of the ligand with a binding argenine. Protein Data Bank ID code 1Z6K (). Distances were measured and presented using Jmol (jmol.sourceforge.net) ().

(A) A scheme of two chiral molecules interacting through achiral methyl groups. (B) Plot of the second-order dispersion energy for aligned spins (blue) and antiparallel spins (red) for the model system R–CH₃…CH₃–R as a function of the carbon–carbon distance, d, for the case of RS interaction (the same spins; red curve) and when the spins are aligned antiparallel in the case of SS interaction (blue curves). (C) Plot of the difference in spin correlation energies, for the same spin and the opposite spin, as a function of intermonomer distance for •CH₃…CH₃• in open shell singlet (blue) and triplet (red) couplings.

(A) The schematic diagram illustrates the electron distribution (blue cloud) in a molecule that does not have a dipole moment before it interacts with another molecule. In this case, the distribution is symmetric. (B) This diagram illustrates the electron distribution where two molecules interact via dispersive forces. The interaction induces an asymmetry in the electrons’ distribution, resulting in an “induced dipole” in each molecule. This charge polarization causes an “induced dipole–induced dipole” interaction. (C) The diagram illustrates the induced dipole interaction of two molecules with the same handedness. As charge q transfers from one side of the molecule to the other, it generates a spin polarization (represented by a red ball and black arrow) of the same spin in the two molecules. The electron density left behind has, therefore, the opposite spin polarization; hence, the interaction between the molecules is characterized by two opposite spins as illustrated by the dotted circle singlet region. (D) When the two interacting molecules are of opposite chirality, the interaction between the molecules is characterized by two spins parallel to each other (in the dotted circle triplet region). Reproduced from ref. .

Gate voltage (V_G)-dependent Hall measurements conducted on devices coated with different oligopeptides. (A) Hall potential measured when the adsorbed layer is either l-SHCH₂CH₂CO-{Ala-Aib}₅-COOH (red) or d-SHCH₂CH₂CO-{Ala-Aib}₅-COOH (blue). The Hall potential was calculated as the difference between the peak responses for each applied gate voltage; ΔV_H+ and ΔV_H− correspond to positive and negative values of I_SD, respectively. More details are in . (B) The dependence of the Hall voltage on V_G is shown for monolayer films of achiral 11-mercapto-undecanoic acid (black), chiral l-SHCH₂CH₂CO-{Ala-Aib}₅-COOH (red), and chiral l-SHCH₂CH₂CO-{Ala-Aib}₇-COOH (green). (C) The time-dependent Hall potential measured with l-SHCH₂CH₂CO-{Ala-Aib}₇-COOH when a voltage of −10 V is applied (indicated in blue) between the gate and the Hall device. On switching the potential off (indicated in green), an opposite signal appears for the chiral molecules as a result of charge flowing back the other way through the monolayer film (in the text). Note that the timescale of the response is controlled by the large capacitance of the measurement method. (D) The time-dependent Hall measurements are shown for various gate voltages. The on and off switching of the gate is marked with blue and green arrows, respectively.

(A) The experimental setup in which a Hall device, coated with a self-assembled organic monolayer, is placed in solution with a G electrode and an inert electrolyte. When an electric potential V_G is applied between the G electrode and the device, the ionic solution is polarized, so that an electric field acts on the adsorbed molecules. As a result, the molecules are polarized because of charge reorganization (partial charges q+ and q−), inducing a charge displacement in the surface region of the device. Because the charge polarization is accompanied by spin polarization (red balls with black arrows in C), a magnetic field that acts on the electrons flowing between the S and D electrodes is also created. The Hall potential V_H, which is formed as a result of the spin magnetization, can be measured as a function of V_G. (B) A schematic diagram illustrating the electrical operation of the device, where I_SD indicates the applied S–D current, V_G is the gate voltage, and V_H is the differential Hall potential across the conductive channel. (C) A scheme describing the spin polarization. When an electric field is applied on a chiral molecule (via V_G), it induces charge reorganization in the molecule, resulting in spin polarization.