PMC

Sample size calculation for sensitivity and specificity analysis for prevalence of disease from 30% to 60%.
Prev = prevalence of disease  H_o = Hypothesis null  H_a = Hypothesis alternative
N1 = The minimum number of sample size for positive disease  N = The minimum number of sample size requirement for total

Sample size calculation for sensitivity and specificity analysis for prevalence of disease from 70% to 90%.
Prev = prevalence of disease  H_o = Hypothesis null  H_a = Hypothesis alternative  N1 = The minimum number of sample size for positive disease  N = The minimum number of sample size requirement for total

Sample size calculation for sensitivity and specificity analysis for prevalence of disease from 5% to 20%.  Prev = prevalence of disease  H_o = Hypothesis null  H_a = Hypothesis alternative
N1 = The minimum number of sample size for positive disease  N = The minimum number of sample size requirement for total